Stem Cell Transplantation for Patients With Multiple Myeloma

G-CSF will be self-administered shot daily for 4 days pre-transplant. Up to 8 doses of G-CSF may be given. G-CSF will also be administered once daily under the skin beginning 5 days after your stem cell infusion until your white blood cell count is high enough

Plerixafor (self-administered shot)prior to the beginning of the stem cell collection. Up to 4 doses of plerixafor may be given.

Stem cell collection begins on day 5 and can last up to 3 days depending on the number collected.

Melphalan chemotherapy 100mg/m2 for 2 days after your admission into the hospital for your ASCT procedure.

Stem cells are thawed and reinfused back into the body via a catheter in the vein.

Basiliximab (20mg) given by IV infusion (through the vein) 20-30 minutes the day after ASCT.

The stem cells collected during apheresis will be counted and treated with CD25 microbeads and processed by a special device called a CliniMACs machine which removes the regulatory T cells from you stem cell product.