Safety Study of 3 mg/mL Baclofen Injection (Intrathecal) Using A Programmable Pump

PHASE3CompletedINTERVENTIONAL
Enrollment

153

Participants

Timeline

Start Date

December 31, 2012

Primary Completion Date

August 31, 2016

Study Completion Date

October 31, 2016

Conditions
Severe Spasticity
Interventions
DRUG

Gablofen® 3 mg/mL (baclofen injection)

This is a prospective twelve-month Phase IIIb clinical safety trial followed by a 2-year, Phase IV study that will be conducted at clinical trial sites that are experienced with the use of intrathecal baclofen. Patients will be followed for the duration of their treatment with Gablofen® (baclofen injection) 3 mg/mL using the SynchroMed® II Programmable Pump or until the study is terminated.

DEVICE

SynchroMed® II Programmable Pump

Intrathecal programmable pump

Trial Locations (13)

33136

Rehabilitation Medicine Department, University of Miami, Miller School of Medicine, Miami

37232

Vanderbilt University Medical Center, Department of Pediatrics, Nashville

43221

The Ohio State University, Columbus

44195

Cleveland Clinic Foundation, Cleveland

48124

Wayne State University, School of Medicine, Dearborn

53226

The Medical College of Wisconsin Department of Physical Medicine and Rehabilitation, Milwaukee

55101

Gillette Children's Specialty Healthcare, Saint Paul

60611

Rehabilitation Institute of Chicago, Chicago

72202

Arkansas Children's Hospital, Little Rock

76104

Cook Children's Health Care System, Fort Worth

77030

TIRR Memorial Hermann, Houston

84132

University of Utah, Division of PM&R, Salt Lake City

92354

Loma Linda University, Loma Linda

All Listed Sponsors
lead

Piramal Critical Care, Ltd.

INDUSTRY

NCT01520545 - Safety Study of 3 mg/mL Baclofen Injection (Intrathecal) Using A Programmable Pump | Biotech Hunter | Biotech Hunter