138
Participants
Start Date
February 22, 2012
Primary Completion Date
August 17, 2020
Study Completion Date
August 1, 2021
18F-Fluoromisonidazole
Undergo FMISO PET/CT (Correlative studies)
Carboplatin
Given IV
Computed Tomography
Undergo FDG PET/CT
Computed Tomography
Undergo FMISO PET/CT (Correlative studies)
External Beam Radiation Therapy
Undergo radiotherapy
Fludeoxyglucose F-18
Undergo FDG PET/CT
Image-Guided Adaptive Radiation Therapy
Undergo individualized adaptive radiotherapy
Laboratory Biomarker Analysis
Correlative studies
Paclitaxel
Given IV
Positron Emission Tomography
Undergo FDG PET/CT
Positron Emission Tomography
Undergo FMISO PET/CT (Correlative studies)
Memorial Sloan Kettering Cancer Center, New York
Memorial Sloan Kettering Sleepy Hollow, Sleepy Hollow
Memorial Sloan Kettering Westchester, Harrison
Memorial Sloan Kettering Nassau, Uniondale
Memorial Sloan Kettering Commack, Commack
Fox Chase Cancer Center, Philadelphia
Temple University Hospital, Philadelphia
Reading Hospital, West Reading
Medical University of South Carolina, Charleston
Augusta University Medical Center, Augusta
University of Mississippi Medical Center, Jackson
The James Graham Brown Cancer Center at University of Louisville, Louisville
Case Western Reserve University, Cleveland
Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland
Hillcrest Hospital Cancer Center, Mayfield Heights
Cleveland Clinic Cancer Center Independence, Independence
Cleveland Clinic Cancer Center Strongsville, Strongsville
Cleveland Clinic Foundation, Cleveland
Cleveland Clinic Wooster Family Health and Surgery Center, Wooster
Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis
University of Michigan Comprehensive Cancer Center, Ann Arbor
Medical College of Wisconsin, Milwaukee
University of Wisconsin Hospital and Clinics, Madison
Rush University Medical Center, Chicago
Washington University School of Medicine, St Louis
Saint Luke's Hospital of Kansas City, Kansas City
University of Oklahoma Health Sciences Center, Oklahoma City
Stanford Cancer Institute Palo Alto, Palo Alto
Memorial Sloan Kettering Basking Ridge, Basking Ridge
McGill University Department of Oncology, Montreal
Saskatoon Cancer Centre, Saskatoon
Collaborators (1)
NRG Oncology
OTHER
National Cancer Institute (NCI)
NIH