Intrapleural Measles Virus Therapy in Patients With Malignant Pleural Mesothelioma

PHASE1CompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

November 30, 2011

Primary Completion Date

April 11, 2019

Study Completion Date

April 11, 2019

Conditions
Recurrent Malignant MesotheliomaStage IA Malignant MesotheliomaStage IB Malignant MesotheliomaStage II Malignant MesotheliomaStage III Malignant MesotheliomaStage IV Malignant Mesothelioma
Interventions
BIOLOGICAL

oncolytic measles virus encoding thyroidal sodium iodide symporter

Given intrapleurally

OTHER

laboratory biomarker analysis

Correlative studies

PROCEDURE

single photon emission computed tomography

Correlative studies

PROCEDURE

computed tomography

Correlative studies

Trial Locations (1)

55905

Mayo Clinic, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Mayo Clinic

OTHER