A Study of Siltuximab (Anti- IL 6 Monoclonal Antibody) in Patients With High-risk Smoldering Multiple Myeloma

PHASE2CompletedINTERVENTIONAL
Enrollment

85

Participants

Timeline

Start Date

March 1, 2012

Primary Completion Date

May 12, 2015

Study Completion Date

August 21, 2019

Conditions
High-risk Smoldering Multiple Myeloma
Interventions
DRUG

Siltuximab

Type=exact, unit=mg/kg, number=15, form=intravenous infusion, route=intravenous use, every 4 weeks until progression to symptomatic multiple myeloma, unacceptable toxicity, withdrawal of consent, or the end of the study.

DRUG

Placebo

Form=intravenous infusion, route=intravenous use route=intravenous, use every 4 weeks until progression to symptomatic multiple myeloma, unacceptable toxicity, withdrawal of consent, or the end of the study.

Trial Locations (40)

Unknown

Chicago

Rockville

Detroit

New York

Kittanning

Philadelphia

Greenville

Dallas

Camperdown

East Melbourne

Randwick

Antwerp

Brussels

Ghent

Dijon

Nantes

Tours

Villejuif

Berlin

Hamburg

Heidelberg

Athens

Ashkelon

Jerusalem

Nahariya

Netanya

Petah Tikva

Tel Aviv

Daejeon

Seoul

Barcelona

Barcleona

Madrid

Salamanca

Valencia

Gothenburg

Linköping

Stockholm

London

Manchester

All Listed Sponsors
lead

Janssen Research & Development, LLC

INDUSTRY

NCT01484275 - A Study of Siltuximab (Anti- IL 6 Monoclonal Antibody) in Patients With High-risk Smoldering Multiple Myeloma | Biotech Hunter | Biotech Hunter