NCT01474915View on ClinicalTrials.gov

Aprepitant Versus Ondansetron in Preoperative Triple-therapy Treatment of Nausea and Vomiting

PHASE4CompletedINTERVENTIONAL
Enrollment

122

Participants

Timeline

Start Date

June 30, 2007

Primary Completion Date

December 31, 2012

Study Completion Date

April 30, 2013

Conditions
Postoperative Nausea and Vomiting (PONV)Nausea
Interventions
DRUG

Aprepitant

Subject will receive 40 mg of Aprepitant versus placebo PO before anesthesia induction

DRUG

Ondansetron

Subject will receive 4 mg of Ondansetron IV versus placebo around anesthesia induction

DRUG

Promethazine

Subject will receive 25 mg of Promethazine IV around anesthesia induction

DRUG

Dexamethasone

Subject will receive 10 mg of Dexamethasone IV around anesthesia induction

Trial Locations (1)

43210

The Ohio State University Wexner Medical Center, Columbus

All Listed Sponsors
lead

Sergio Bergese

OTHER

NCT01474915 - Aprepitant Versus Ondansetron in Preoperative Triple-therapy Treatment of Nausea and Vomiting | Biotech Hunter | Biotech Hunter