Study of Everolimus and Low-dose Cyclophosphamide in Patients With Metastatic Renal Cell Cancer

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

96

Participants

Timeline

Start Date

October 31, 2011

Primary Completion Date

January 31, 2017

Study Completion Date

January 31, 2017

Conditions
Metastatic Renal Cell Cancer
Interventions
DRUG

Everolimus

Patients will be treated with low-dose oral cyclophosphamide (8 different dose levels and schedules) in combination with fixed dose (10 mg) everolimus in patients with mRCC.

Trial Locations (13)

Unknown

Medisch Centrum Alkmaar, Alkmaar

NKI-AVL, Amsterdam

Universitair Medisch Centrum Groningen, Groningen

Spaarne Ziekenhuis Hoofddorp, Hoofddorp

Medisch Centrum Leeuwarden, Leeuwarden

University Hospital Maastricht, Maastricht

St. Antonius Ziekenhuis, Nieuwegein

UMC St Radboud Nijmegen, Nijmegen

Sint Franciscus Gasthuis Rotterdam, Rotterdam

Haga Ziekenhuis, The Hague

Medisch Centrum Haaglanden, The Hague

Isala Klinieken Zwolle, Zwolle

1081 HV

VU University Medical Center, Amsterdam

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Dutch Cancer Society

OTHER

collaborator

Novartis

INDUSTRY

lead

Hans J. van der Vliet, MD, PhD

OTHER