NCT01458600 - Adjuvant Treatment of Graves´ Ophthalmopathy With NSAID (aGO Study) | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

September 30, 2006

Primary Completion Date

February 29, 2016

Study Completion Date

February 29, 2016

Conditions

Graves´ Disease

Interventions

DRUG

Diclofenac

T Diclofenac 50 mg twice daily for 12 months

DRUG

Methimazole

T Methimazole 5 mg 3x2 for 18 months

DRUG

L-thyroxin

L-thyroxin approximately 100 to 200 micrograms/day. The dose is adjusted to reach euthyroidism during concomitant treatment with methimazole for 18 months

DRUG

Propranolol

T Propronalol 40mg 1x1-3 during during 1-3 weeks until the patient has responded to thyrostatics

DRUG

Metoprolol

T Metoprolol 50 mg 1x3 for 1-3 weeks until the patient has responded to thyrostatics

Trial Locations (3)

Unknown

Departmenty of Endocrinology, Skane University Hospital, Malmo

Department of Endocrinology, Karolinska Hospital, Stockholm

Department of Internal Medicine, section of Endocrinology, Sodersjukhuset, Stockholm