NCT01456325 - A Study of Onartuzumab (MetMAb) in Combination With Tarceva (Erlotinib) in Participants With Met Diagnostic-Positive Non-Small Cell Lung Cancer Who Have Received Chemotherapy For Advanced or Metastatic Disease (MetLung) | Biotech Hunter

Enrollment

494

Participants

Timeline

Start Date

January 31, 2012

Primary Completion Date

January 31, 2016

Study Completion Date

January 31, 2016

Conditions

Non-Squamous Non-Small Cell Lung Cancer

Interventions

DRUG

Erlotinib

Participants will receive erlotinib 150 mg tablet orally once daily from Day 1, Cycle 1.

DRUG

Onartuzumab (MetMab)

Participants will receive onartuzumab 15 mg/kg IV infusion on Day 1 of every 3-week cycle.

DRUG

Placebo

Participants will receive onartuzumab matching placebo on Day 1 of every 3-week cycle.

Trial Locations (213)

0

Santiago

8

Dublin

100

Taipei

500

Changhua

813

Kaohsiung City

1200

Brussels

1878

Quilmes

2050

Camperdown

2193

Johannesburg

2196

Sandton

2298

Waratah

3050

Parkville

3529

Miskolc

3780

Edelény

4000

Liège

4032

Chermside

5000

Namur

5041

Adelaide

6000

Gilly (Charleroi)

9000

Ghent

9301

Bloemfontein

9700

Szombathely

10000

Zagreb

10043

Orbassano

11000

Belgrade

11080

Belgrade

13210

Syracuse

13915

Marseille

14076

Caen

14165

Berlin

15232

Pittsburgh

16132

Genoa

18009

Cherkassy

19104

Philadelphia

20000

Dubrovnik

20089

Rozzano

20141

Milan

20900

Monza

21075

Hamburg

21201

Baltimore

21231

Baltimore

21237

Baltimore

21401

Annapolis

22927

Großhansdorf

24014

Roanoke

24201

Bristol

25030

Besançon

26121

Oldenburg

27514

Chapel Hill

28007

Madrid

28034

Madrid

28050

Madrid

28222

Madrid

29210

Columbia

29403

Charleston

32207

Jacksonville

32256

Jacksonville

33081

Aviano

33486

Boca Raton

33761

Clearwater

33901

Fort Myers

34000

Kragujevac

34295

Montpellier

37203

Nashville

37404

Chattanooga

37909

Knoxville

40000

Čakovec

40005

Sumy

40207

Louisville

41013

Seville

41014

Valencia

43210

Columbus

43219

Columbus

44106

Cleveland

44718

Canton

44805

Saint-Herblain

48106

Ann Arbor

49100

Petah Tikva

49102

Dnipropetrovsk

51101

Sioux City

52100

Pula

52722

Bettendorf

54511

Vandœuvre-lès-Nancy

55043

Lido di Camaiore

55131

Mainz

55805

Duluth

58013

Chernivtsi

60121

Ancona

60637

Chicago

61801

Urbana

63110

St Louis

68114

Omaha

69040

Zaporizhzhya

69126

Heidelberg

75390

Dallas

75970

Paris

76100

Rehovot

76104

Fort Worth

76137

Karlsruhe

77030

Houston

78052

Villingen-Schwenningen

80336

München

85224

Chandler

86021

Poitiers

87042

Limoges

87401

Farmington

89081

Ulm

89502

Reno

92108

San Diego

92151

Suresnes

92868

Orange

93053

Regensburg

94080

South San Francisco

94115

San Francisco

94545

Hayward

94589

Vallejo

94596

Walnut Creek

94611

Oakland

95051

Santa Clara

95119

San Jose

95355

Modesto

95661

Roseville

95817

Sacramento

95825

Sacramento

99437

Bad Berka

153040

Ivanovo

189646

Saint Petersburg

197022

Saint Petersburg

197101

Saint Petersburg

350040

Krasnodar

634050

Tomsk

644013

Omsk

4428164

Kfar Saba

4810469

Temuco

4959381

Haifa

5262100

Ramat Gan

8410101

Beersheba

9372212

Jerusalem

02114

Boston

02115

Boston

01107

Springfield

B1900BAJ

La Plata

S3000FFU

Santa Fe

41820-021

Salvador/BA

95900-000

Lajeado

93510-250

Novo Hamburgo

17210-080

Jaú

08270-070

São Paulo

18030-005

Sorocaba

E2L 4L2

Saint John

P6A 2C4

Sault Ste. Marie

M4N 3M5

Toronto

M5G 2M9

Toronto

H3A 1A1

Montreal

J4B 5Z7

Montreal

Providencia

Santiago

38 043

Grenoble

Unknown

Pokfulam

Shatin

Cork

Poznan

91120-01

Jerusalem

06123

Perugia

464-8681

Aichi

277-8577

Chiba

791-0280

Ehime

811-1395

Fukuoka

812-8582

Fukuoka

650-0047

Hyōgo

673-8553

Hyōgo

236-0051

Kanagawa

606-8507

Kyoto

980-8574

Miyagi

981-1293

Miyagi

700-8558

Okayama

710-8602

Okayama

534-0021

Osaka

537-8511

Osaka

589-8511

Osaka

591-8555

Osaka

362-0806

Saitama

411-8777

Shizuoka

104-0045

Tokyo

113-8677

Tokyo

135-8550

Tokyo

160-0023

Tokyo

173-8605

Tokyo

755-0241

Yamaguchi

1081 HV

Amsterdam

9700 RB

Groningen

6229 HX

Maastricht

L27

Lima

Lima 1

Lima

Lima 27

Lima

80-952

Gdansk

31-531

Krakow

93-509

Lodz

10-357

Olsztyn

443-380

Gyeonggi-do

05505

Seoul

06591

Seoul

120-752

Seoul

08035

Barcelona

08036

Barcelona

08041

Barcelona

08916

Barcelona

08208

Sabadell

BT9 7AB

Belfast

DN33 2BA

Grimsby

LE1 5WW

Leicester

SE1 9RT

London

SW10 9NH

London

M2O 4BX

Manchester