2,354
Participants
Start Date
September 30, 2011
Primary Completion Date
November 30, 2015
Study Completion Date
January 31, 2016
Roflumilast
Roflumilast 500 µg, oral administration, once per day
Placebo
Dose-matched placebo, oral administration, once per day.
Forest Investigative Site 725, Taipei
Forest Investigative Site 723, Kaohsiung Hsien
Forest Investigative Site 565, Manila
Forest Investigative Site 562, Quezon City
Forest Investigative Site 564, Quezon City
Forest Investigative Site 566, Quezon City
Forest Investigative Site 561, Quezon City
Forest Investigative Site 563, Pasig
Forest Investigative Site 410, San Juan Bautista
Forest Investigative Site 405, La Plata
Forest Investigative Site 417, La Plata
Forest Investigative Site 408, Santa Fe
Forest Investigative Site 698, Kyiv
Forest Investigative Site 683, Kyiv
Forest Investigative Site 684, Kyiv
Forest Investigative Site 687, Kyiv
Forest Investigative Site 685, Kyiv
Forest Investigative Site 569, Cavite
Forest Investigative Site 567, Iloilo City
Forest Investigative Site 568, Iloilo City
Forest Investigative Site 420, Mendoza
Forest Investigative Site 071, New York
Forest Investigative Site 664, Bangkok
Forest Investigative Site 586, Bucharest
Forest Investigative Site 622, Belgrade
Forest Investigative Site 623, Belgrade
Forest Investigative Site 624, Belgrade
Forest Investigative Site 625, Belgrade
Forest Investigative Site 663, Bangkok
Forest Investigative Site 641, Cadiz
Forest Investigative Site 199, Great Neck
Forest Investigative Site 226, Brooklyn
Forest Investigative Site 722, Taipei
Forest Investigative Site 066, Syracuse
Forest Investigative Site 158, West Seneca
Forest Investigative Site 013, Rochester
Forest Investigative Site 340, Beaver
Forest Investigative Site 336, Pittsburgh
Forest Investigative Site 364, Pittsburgh
Forest Investigative Site 344, Pittsburgh
Forest Investigative Site 064, Uniontown
Forest Investigative Site 062, Erie
Forest Investigative Site 086, Altoona
Forest Investigative Site 010, Tipton
Forest Investigative Site 644, Salt
Forest Investigative Site 699, Cherkasy
Forest Investigative Site 629, Knez-Selo
Forest Investigative Site 647, Loja
Forest Investigative Site 230, Philadelphia
Forest Investigative Site 205, Philadelphia
Forest Investigative Site 120, Downingtown
Forest Investigative Site 277, Norristown
Forest Investigative Site 124, Newark
Forest Investigative Site 707, Vinnitsa
Forest Investigative Site 020, Columbia
Forest Investigative Site 072, Towson
Forest Investigative Site 627, Kamenitz
Forest Investigative Site 248, Baltimore
Forest Investigative Site 202, Richmond
Forest Investigative Site 231, Richmond
Forest Investigative Site 045, Richmond
Forest Investigative Site 125, Abingdon
Forest Investigative Site 502, Kuantan
Forest Investigative Site 335, Charleston
Forest Investigative Site 319, Morgantown
Forest Investigative Site 282, Winston-Salem
Forest Investigative Site 314, Winston-Salem
Forest Investigative Site 193, Burlington
Forest Investigative Site 019, Elizabeth City
Forest Investigative Site 318, Shelby
Forest Investigative Site 078, Shelby
Forest Investigative Site 142, Charlotte
Forest Investigative Site 259, Charlotte
Forest Investigative Site 176, Wilmington
Forest Investigative Site 313, Asheville
Forest Investigative Site 021, Spartanburg
Forest Investigative Site 233, Gaffney
Forest Investigative Site 012, Union
Forest Investigative Site 305, Charleston
Forest Investigative Site 110, Greenville
Forest Investigative Site 093, Easley
Forest Investigative Site 300, Pelzer
Forest Investigative Site 257, Fort Mill
Forest Investigative Site 204, Rock Hill
Forest Investigative Site 030, Lawrenceville
Forest Investigative Site 042, Duluth
Forest Investigative Site 103, Canton
Forest Investigative Site 321, Woodstock
Forest Investigative Site 587, Bucharest
Forest Investigative Site 140, Gainesville
Forest Investigative Site 292, Dawsonville
Forest Investigative Site 588, Bucharest
Forest Investigative Site 161, Ponte Vedra
Forest Investigative Site 087, Port Orange
Forest Investigative Site 187, Ormond Beach
Forest Investigative Site 023, Jacksonville
Forest Investigative Site 239, DeFuniak Springs
Forest Investigative Site 069, Pensacola
Forest Investigative Site 165, Fort Walton Beach
Forest Investigative Site 102, Gainesville
Forest Investigative Site 166, Chiefland
Forest Investigative Site 011, Winter Park
Forest Investigative Site 348, Winter Park
Forest Investigative Site 004, Orlando
Forest Investigative Site 027, Miami
Forest Investigative Site 003, Hollywood
Forest Investigative Site 291, Coral Gables
Forest Investigative Site 229, Miami
Forest Investigative Site 115, Miami
Forest Investigative Site 339, Miami
Forest Investigative Site 002, Tamarac
Forest Investigative Site 001, Fort Lauderdale
Forest Investigative Site 196, Brandon
Forest Investigative Site 224, Brandon
Forest Investigative Site 358, Brandon
Forest Investigative Site 287, Tampa
Forest Investigative Site 052, Tampa
Forest Investigative Site 121, St. Petersburg
Forest Investigative Site 357, St. Petersburg
Forest Investigative Site 111, Clearwater
Forest Investigative Site 123, Clearwater
Forest Investigative Site 628, Kragujevac
Forest Investigative Site 092, Naples
Forest Investigative Site 077, Kissimmee
Forest Investigative Site 330, Kissimmee
Forest Investigative Site 109, Saint Cloud
Forest Investigative Site 065, Athens
Forest Investigative Site 131, Florence
Forest Investigative Site 706, Poltava
Forest Investigative Site 081, Anniston
Forest Investigative Site 073, Mobile
Forest Investigative Site 253, Shelbyville
Forest Investigative Site 050, Fayetteville
Forest Investigative Site 223, Bristol
Forest Investigative Site 695, Sumy
Forest Investigative Site 661, Muang
Forest Investigative Site 088, Louisville
Forest Investigative Site 068, Lexington
Forest Investigative Site 075, Crescent Springs
Forest Investigative Site 351, Hazard
Forest Investigative Site 051, Bowling Green
Forest Investigative Site 053, Owensboro
Forest Investigative Site 009, Columbus
Forest Investigative Site 059, Marion
Forest Investigative Site 154, Marion
Forest Investigative Site 346, Toledo
Forest Investigative Site 105, Zanesville
Forest Investigative Site 524, Guadalajara
Forest Investigative Site 164, Canton
Forest Investigative Site 149, Cincinnati
Forest Investigative Site 061, Cincinnati
Forest Investigative Site 040, Cincinnati
Forest Investigative Site 280, Cincinnati
Forest Investigative Site 353, Dayton
Forest Investigative Site 263, Elwood
Forest Investigative Site 293, Michigan City
Forest Investigative Site 264, Muncie
Forest Investigative Site 342, Lafayette
Forest Investigative Site 157, Ann Arbor
Forest Investigative Site 063, Livonia
Forest Investigative Site 341, Detroit
Forest Investigative Site 328, Kalamazoo
Forest Investigative Site 691, Dnipropetrovsk
Forest Investigative Site 322, Saint Joseph
Forest Investigative Site 584, Bucharest
Forest Investigative Site 582, Bucharest
Forest Investigative Site 501, Kuala Lumpur
Forest Investigative Site 135, Council Bluffs
Forest Investigative Site 256, Iowa City
Forest Investigative Site 146, West Allis
Forest Investigative Site 708, Mykolayiv
Forest Investigative Site 056, Fridley
Forest Investigative Site 303, Edina
Forest Investigative Site 082, Rochester
Forest Investigative Site 058, Rapid City
Forest Investigative Site 504, Kuala Lumpur
Forest Investigative Site 333, Butte
Forest Investigative Site 029, Missoula
Forest Investigative Site 136, Elk Grove Village
Forest Investigative Site 139, Oak Lawn
Forest Investigative Site 201, Bolingbrook
Forest Investigative Site 206, Downers Grove
Forest Investigative Site 697, Kharkiv
Forest Investigative Site 693, Kharkiv
Forest Investigative Site 682, Kharkiv
Forest Investigative Site 724, Puzih City
Forest Investigative Site 227, Peoria
Forest Investigative Site 334, Springfield
Forest Investigative Site 033, Chesterfield
Forest Investigative Site 186, St Louis
Forest Investigative Site 288, St Louis
Forest Investigative Site 098, Saint Charles
Forest Investigative Site 521, Monterrey
Forest Investigative Site 522, Monterrey
Forest Investigative Site 117, Springfield
Forest Investigative Site 461, Chieti
Forest Investigative Site 214, Olathe
Forest Investigative Site 316, Topeka
Forest Investigative Site 301, Wichita
Forest Investigative Site 267, Fremont
Forest Investigative Site 337, Fremont
Forest Investigative Site 505, Batu Caves
Forest Investigative Site 345, Omaha
Forest Investigative Site 197, Bellevue
Forest Investigative Site 315, Lincoln
Forest Investigative Site 108, Lincoln
Forest Investigative Site 696, Zaporizhzhya
Forest Investigative Site 694, Zaporizhzhya
Forest Investigative Site 705, Zaporizhzhya
Forest Investigative Site 688, Zaporizhzhia
Forest Investigative Site 273, Lafayette
Forest Investigative Site 070, Opelousas
Forest Investigative Site 097, Sunset
Forest Investigative Site 101, Little Rock
Forest Investigative Site 208, Fort Smith
Forest Investigative Site 167, Oklahoma City
Forest Investigative Site 281, Oklahoma City
Forest Investigative Site 236, Tulsa
Forest Investigative Site 090, Corsicana
Forest Investigative Site 172, Dallas
Forest Investigative Site 232, Longview
Forest Investigative Site 049, Tyler
Forest Investigative Site 024, Arlington
Forest Investigative Site 690, Ivano-Frankivsk
Forest Investigative Site 237, Houston
Forest Investigative Site 271, Houston
Forest Investigative Site 370, Houston
Forest Investigative Site 195, Houston
Forest Investigative Site 312, Houston
Forest Investigative Site 332, Huntsville
Forest Investigative Site 177, Boerne
Forest Investigative Site 681, Lviv
Forest Investigative Site 692, Donetsk
Forest Investigative Site 689, Donetsk
Forest Investigative Site 119, Eagle
Forest Investigative Site 008, Coeur d'Alene
Forest Investigative Site 034, Phoenix
Forest Investigative Site 188, Phoenix
Forest Investigative Site 211, Phoenix
Forest Investigative Site 247, Phoenix
Forest Investigative Site 272, Mesa
Forest Investigative Site 091, Peoria
Forest Investigative Site 079, Henderson
Forest Investigative Site 270, Henderson
Forest Investigative Site 085, Los Angeles
Forest Investigative Site 241, Los Angeles
Forest Investigative Site 662, Hat Yai
Forest Investigative Site 209, Torrance
Forest Investigative Site 074, Bellflower
Forest Investigative Site 297, Lakewood
Forest Investigative Site 116, Long Beach
Forest Investigative Site 299, Northridge
Forest Investigative Site 352, San Diego
Forest Investigative Site 038, San Diego
Forest Investigative Site 025, Riverside
Forest Investigative Site 245, Fullerton
Forest Investigative Site 310, Garden Grove
Forest Investigative Site 268, Pismo Beach
Forest Investigative Site 060, Fresno
Forest Investigative Site 329, Fresno
Forest Investigative Site 213, Palo Alto
Forest Investigative Site 326, San Jose
Forest Investigative Site 143, Roseville
Forest Investigative Site 104, Sacramento
Forest Investigative Site 526, Mérida
Forest Investigative Site 289, Portland
Forest Investigative Site 218, Portland
Forest Investigative Site 285, Medford
Forest Investigative Site 217, Tacoma
Forest Investigative Site 184, Spokane
Forest Investigative Site 174, Spokane
Forest Investigative Site 442, Bogotá
Forest Investigative Site 443, Bogotá
Forest Investigative Site 617, Moscow
Forest Investigative Site 620, Yaroslavl
Forest Investigative Site 606, Saint Petersburg
Forest Investigative Site 612, Saint Petersburg
Forest Investigative Site 619, Saint Petersburg
Forest Investigative Site 604, Saint Petersburg
Forest Investigative Site 611, Saint Petersburg
Forest Investigative Site 610, Saint Petersburg
Forest Investigative Site 601, Saint Petersburg
Forest Investigative Site 600, Saint Petersburg
Forest Investigative Site 609, Krasnodar
Forest Investigative Site 602, Kazan'
Forest Investigative Site 585, Brasov
Forest Investigative Site 605, Novosibirsk
Forest Investigative Site 607, Tomsk
Forest Investigative Site 618, Kemerovo
Forest Investigative Site 608, Barnaul
Forest Investigative Site 614, Krasnoyarsk
Forest Investigative Site 581, Iași
Forest Investigative Site 583, Iași
Forest Investigative Site 421, Talcahuano
Forest Investigative Site 331, Stamford
Forest Investigative Site 017, Waterbury
Forest Investigative Site 128, Lewiston
Forest Investigative Site 106, Fall River
Forest Investigative Site 044, North Dartmouth
Forest Investigative Site 350, Pittsfield
Forest Investigative Site 067, Cherry Hill
Forest Investigative Site 327, Clifton
Forest Investigative Site 144, Hackensack
Forest Investigative Site 317, Summit
Forest Investigative Site 228, Johnston
Forest Investigative Site 283, Lincoln
Forest Investigative Site 365, Providence
Forest Investigative Site 181, Colchester
Forest Investigative Site 403, Buenos Aires
Forest Investigative Site 418, Ciudad Autonoma de Buenos Aires
Forest Investigative Site 402, Florida
Forest Investigative Site 406, Lanús Este
Forest Investigative Site 413, Mar del Plata
Forest Investigative Site 407, Paraná
Forest Investigative Site 404, Mendoza
Forest Investigative Site 412, Rosario
Forest Investigative Site 409, Rosario
Forest Investigative Site 411, Buenos Aires
Forest Investigative Site 414, Buenos Aires
Forest Investigative Site 419, Buenos Aires
Forest Investigative Site 416, Buenos Aires
Forest Investigative Site 415, Derqui Pilar - Buenos Aires
Forest Investigative Site 401, San Miguel de Tucumán
Forest Investigative Site 235, Calgary
Forest Investigative Site 162, North Vancouver
Forest Investigative Site 302, Burlington
Forest Investigative Site 185, Montreal
Forest Investigative Site 127, Saskatoon
Forest Investigative Site 464, Roma
Forest Investigative Site 543, Bellavista
Forest Investigative Site 550, Lima
Forest Investigative Site 551, Lima
Forest Investigative Site 545, Lima
Forest Investigative Site 546, Lima
Forest Investigative Site 549, Lima
Forest Investigative Site 544, Lima
Forest Investigative Site 541, Pueblo Libre
Forest Investigative Site 709, Kremenchuk
Lead Sponsor
AstraZeneca
INDUSTRY