Low-level Laser Therapy to Prevent Oral Mucositis in Head and Neck Patients

PHASE3CompletedINTERVENTIONAL
Enrollment

94

Participants

Timeline

Start Date

June 30, 2007

Primary Completion Date

June 30, 2008

Study Completion Date

December 31, 2010

Conditions
Squamous Cell Carcinoma of NasopharynxSquamous Cell Carcinoma of OropharynxSquamous Cell Carcinoma of Hypopharynx
Interventions
DEVICE

Low Level Laser Therapy- (DMC, São Paulo, Brazil)

Diode laser (DMC,São Paulo, Brazil) InGaAlP (indium phosphide, gallium and aluminum), with 100 mW, 4J/cm ², with an area of 0.24 cm ². The laser was daily applied by a dentist and touched the mucosa of the lips, right and left buccal mucosa, left and right lateral tongue border, buccal floor and ventral tongue, totaling nine points per region.

DEVICE

Placebo (DMC, São Paulo, Brazil)

The placebo (DMC, São Paulo, Brazil) was daily applied by a dentist and touched the mucosa of the lips, right and left buccal mucosa, left and right lateral tongue border, buccal floor and ventral tongue, totaling nine points per region.Patients in the placebo group received the same treatment during the same time, but in this case the laser tip produced no light.

Trial Locations (1)

20231-050

Instituto Nacional de Cancer, Rio de Janeiro

All Listed Sponsors
lead

Instituto Nacional de Cancer, Brazil

OTHER_GOV

NCT01439724 - Low-level Laser Therapy to Prevent Oral Mucositis in Head and Neck Patients | Biotech Hunter | Biotech Hunter