Single Versus Combination Therapy in Acute Tocolysis

PHASE2CompletedINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

April 30, 2007

Primary Completion Date

September 30, 2010

Study Completion Date

March 31, 2011

Conditions
Preterm Labour
Interventions
DRUG

Atosiban

Atosiban was given as a bolus (6.7 mg. IV) over 1 min then an infusion of 18 mg/hr for 3 hrs followed by 6 mg/hr for 48 hrs.

DRUG

Atosiban and nifedipine

This group were given simultaneously as follows:Atosiban was given as a bolus (6.7 mg. IV) over 1 min then an infusion of 18 mg/hr for 3 hrs followed by 6 mg/hr for 48 hrs.Nifedipine was given in the dose of 10 mg orally every 15 min till uterine quiescence was achieved (\<4 contractions/hr). Maximum dose was 40 mg in the first hour then maintenance dose of 10 mg every 4-6 h for 48 hrs was given.

Trial Locations (2)

15258

Department of obstetrics and Gynecology, Tawam Hospital, Al Ain City

Tawam Hospital, Al Ain City

All Listed Sponsors
lead

Tawam Hospital

OTHER

NCT01429545 - Single Versus Combination Therapy in Acute Tocolysis | Biotech Hunter | Biotech Hunter