NCT01422148View on ClinicalTrials.gov

Minocycline Plus Amiodarone Versus Amiodarone Alone for the Prevention of Atrial Fibrillation After Cardiac Surgery

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

July 31, 2025

Primary Completion Date

January 24, 2027

Study Completion Date

January 24, 2028

Conditions
Atrial Fibrillation
Interventions
DRUG

Amiodarone

oral amiodarone (400 mg twice daily for 7 days, then 200 mg twice daily for the next 7 days

DRUG

Minocycline

intravenous minocycline 100 mg daily x 5 days starting intra-operatively combined with oral amiodarone (400 mg twice daily for 7 days, then 200 mg twice daily for the next 7 days

Trial Locations (1)

02176

Abdallah Alameddine, Melrose

All Listed Sponsors
lead

Baystate Medical Center

OTHER