37
Participants
Start Date
July 12, 2012
Primary Completion Date
February 13, 2024
Study Completion Date
February 13, 2028
Standard Salvage Radiation Treatment (SSRT)
A total dose of 68 Gy delivered in 34 fractions to the Clinical Target Volume (CTV), 51 Gy in 34 fractions can be given to the pelvic nodes.
Mapped Tumor Salvage RT (MTSRT)
Dose escalation to the imaging or Dynamic Contrast Enhanced MRI (DCE-MRI)-defined dominant region(s) by dose painting at 2.25 Gy per fraction, while the rest of the Clinical Target Volume (CTV) receives 2.0 Gy a fraction to 68 Gy. The mapped tumor (MT) boost region will receive an absolute dose of 76.5 Gy. Assuming an α/β ratio of 3.0, this would be equivalent to 80 Gy in 2.0 Gy fractions.
University of Miami, Miami
University of Miami
OTHER