A Study to Assess the Effect Tasimelteon on the Cytochrome P450 3A4 and 2C8 Enzymes in Healthy Subjects

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

August 31, 2011

Primary Completion Date

August 31, 2011

Study Completion Date

August 31, 2011

Conditions

Healthy Volunteers

Interventions

DRUG

Tasimelteon

20mg daily dosing, Days 4-20

DRUG

Rosiglitazone

4mg, single dose, Days 3 and 20

DRUG

Midazolam

10mg, single dose, Days 1 and 18

Trial Locations (1)

Bio-Kinetic Clinical Applications, Springfield