A Prospective, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate Efficacy and Safety of Atrasentan, Including Thoracic Bioimpedance, in Type 2 Diabetic Subjects With Nephropathy

PHASE2CompletedINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

August 31, 2011

Primary Completion Date

September 30, 2012

Study Completion Date

September 30, 2012

Conditions
Chronic Kidney DiseaseDiabetic Nephropathy
Interventions
DRUG

Atrasentan

Subjects will take two tablets daily of either low dose Atrasentan QD or high dose Atrasentan QD for 8 weeks during the treatment period.

DRUG

Placebo

Subjects will take two tablets daily of placebo QD for 8 weeks during the treatment period.

Trial Locations (28)

11355

Site Reference ID/Investigator# 55543, Flushing

12206

Site Reference ID/Investigator# 64023, Albany

15224

Site Reference ID/Investigator# 61742, Pittsburgh

18017

Site Reference ID/Investigator# 54123, Bethlehem

30901

Site Reference ID/Investigator# 68986, Augusta

33021

Site Reference ID/Investigator# 56642, Hollywood

33472

Site Reference ID/Investigator# 56924, Boynton Beach

37408

Site Reference ID/Investigator# 54132, Chattanooga

44094

Site Reference ID/Investigator# 58147, Willoughby Hills

48341

Site Reference ID/Investigator# 68982, Pontiac

58103

Site Reference ID/Investigator# 54164, Fargo

60611

Site Reference ID/Investigator# 56644, Chicago

70808

Site Reference ID/Investigator# 54129, Baton Rouge

75231

Site Reference ID/Investigator# 54108, Dallas

75402

Site Reference ID/Investigator# 54126, Greenville

76180

Site Reference ID/Investigator# 54116, North Richland Hills

77024

Site Reference ID/Investigator# 58153, Houston

77099

Site Reference ID/Investigator# 54110, Houston

80209

Site Reference ID/Investigator# 54121, Denver

85032

Site Reference ID/Investigator# 58144, Phoenix

85284

Site Reference ID/Investigator# 71034, Tempe

90048

Site Reference ID/Investigator# 70173, Los Angeles

91702

Site Reference ID/Investigator# 56927, Azusa

Site Reference ID/Investigator# 70793, Azusa

91910

Site Reference ID/Investigator# 64027, Chula Vista

91942

Site Reference ID/Investigator# 64026, La Mesa

94520

Site Reference ID/Investigator# 54120, Concord

98383

Site Reference ID/Investigator# 54173, Silverdale

All Listed Sponsors
lead

AbbVie (prior sponsor, Abbott)

INDUSTRY

NCT01399580 - A Prospective, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate Efficacy and Safety of Atrasentan, Including Thoracic Bioimpedance, in Type 2 Diabetic Subjects With Nephropathy | Biotech Hunter | Biotech Hunter