PET in Breast Cancer Receiving Neoadjuvant Chemotherapy

PHASE2CompletedINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

July 31, 2006

Primary Completion Date

September 30, 2008

Study Completion Date

June 30, 2011

Conditions
Breast Cancer
Interventions
DRUG

docetaxel (75 mg/m2) and doxorubicin (50 mg/m2)

The chemotherapeutic regimen consisted of docetaxel (75 mg/m2) and doxorubicin (50 mg/m2) by intravenous infusion every 3 weeks. After three cycles of neoadjuvant chemotherapy, the patients were re-evaluated for response and underwent curative surgery. Radiologic response was evaluated using breast magnetic resonance imaging (MRI) for the primary breast tumor and chest computed tomography (CT) for axillary, supraclavicular, internal mammary lymph nodes with RECIST criteria. Both breast MRI and chest CT were performed in all the 78 patients. Subsequently, the patients received three more cycles of docetaxel and doxorubicin as an adjuvant chemotherapy, followed by hormonal or radiation therapy, if indicated.

All Listed Sponsors
lead

Seoul National University Hospital

OTHER

NCT01396655 - PET in Breast Cancer Receiving Neoadjuvant Chemotherapy | Biotech Hunter | Biotech Hunter