Use of N-Acetylcysteine During Liver Procurement

PHASE2CompletedINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

December 31, 2006

Primary Completion Date

July 31, 2009

Study Completion Date

July 31, 2009

Conditions
Liver FailureLiver Failure, AcuteLiver DiseasesCarcinoma, HepatocellularLiver Neoplasms
Interventions
DRUG

N-acetylcystein

15 min systemic NAC infusion of the donor (30 mg/kg, maximum dose 3000 mg) diluted into 500 ml 5 % glucose solution, 30 min before initiating the liver harvesting procedure, and a loco-regional infusion (150 mg/kg of estimated liver weight, maximum dose 300 mg) into the portal vein 5 min before cross-clamping.

Trial Locations (1)

35128

Azienda Ospedaliera di Padova, Padua

All Listed Sponsors
lead

Azienda Ospedaliera di Padova

OTHER

NCT01394497 - Use of N-Acetylcysteine During Liver Procurement | Biotech Hunter | Biotech Hunter