Safety Study of R(+)Pramipexole to Treat Early Alzheimer's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

July 31, 2011

Primary Completion Date

January 31, 2014

Study Completion Date

April 30, 2014

Conditions
Alzheimer's Disease
Interventions
DRUG

R-pramipexole

R-pramipexole will be taken as a liquid and start at one teaspoon (5 ml) twice a day for a total dose of 100 mg/day. After 4 weeks, the dose will double (two teaspoons twice a day, or a total of 200mg/day). Four weeks later the dose will be increased again to 2 1/2 teaspoons twice a day (total of 300mg/day) where it will remain for the remaining 16 weeks of study treatment. Prior to each increase, participants and their study partners will be interviewed regarding any possible side effects or problems. These findings will be discussed with the physician prior to increasing the study drug dose. The dose will only increase if the participant is not having side effects.

Trial Locations (1)

66160

University of Kansas Medical Center, Kansas City

All Listed Sponsors
collaborator

University of Kansas

OTHER

collaborator

Alzheimer's Drug Discovery Foundation

OTHER

lead

Virginia Commonwealth University

OTHER

NCT01388478 - Safety Study of R(+)Pramipexole to Treat Early Alzheimer's Disease | Biotech Hunter | Biotech Hunter