Choosing Opioid Management for Pain and Analyzing Acute Chest Syndrome (ACS) Rates Equally

PHASE3CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

May 26, 2010

Primary Completion Date

January 14, 2014

Study Completion Date

October 18, 2016

Conditions
PainSickle Cell Disease
Interventions
DRUG

Morphine

"Loading Dose: 0.1mg/kg. May repeat every 15 min up to a maximum of 3 total doses until pain controlled.~Continuous rate: 0.01-0.04mg/kg/hr (titrated to comfort level) PCA dose 0.01-0.03 mg/kg maximum 1.6 mg/dose 4 hour dose limit 0.24-0.3 mg/kg (Maximum dosing will not exceed 25 mg/4 hrs)."

DRUG

Nubain

"Loading Dose: 0.1mg/kg. May repeat every 15 min up to a maximum of 3 total doses until pain controlled.~Continuous rate: 0.01-0.04mg/kg/hr (titrated to comfort level) PCA dose 0.01-0.03 mg/kg maximum 1.6 mg/dose 4 hour dose limit 0.24-0.3 mg/kg (Maximum dosing will not exceed 25 mg/4 hrs)."

Trial Locations (1)

30303

Children's Healthcare of Atlanta, Atlanta

All Listed Sponsors
collaborator

Atlanta Clinical and Translational Science Institute

OTHER

lead

Children's Healthcare of Atlanta

OTHER