134
Participants
Start Date
December 31, 2011
Primary Completion Date
January 31, 2018
Study Completion Date
January 31, 2018
Phenoxybenzamine
Starting dosage of phenoxybenzamine in hypertensive subjects:20 mg q.d. (=10 mg b.i.d.) and in normotensive subjects 10 mg q.d. (in the evening). Dose escalation until blood pressure targets are reached, with a maximum dose of 140 mg q.d. (=70 mg b.i.d.)
Doxazosin
Starting dosage of doxazosine in hypertensive subjects:8 mg q.d. (=4 mg b.i.d.)and in normotensive subjects starting dose 4 mg q.d. (in the evening). Dose escalation until blood pressure targets are reached, with a maximum dose of 48 mg q.d. .(=24 mg b.i.d.)
Department of Endocrinology, University Medical Center Groningen, Groningen
Collaborators (3)
Radboud University Medical Center
OTHER
UMC Utrecht
OTHER
VU University of Amsterdam
OTHER
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
OTHER
Leiden University Medical Center
OTHER
Erasmus Medical Center
OTHER
Maastricht University Medical Center
OTHER
St. Antonius Hospital
OTHER
Medisch Spectrum Twente
OTHER
Maxima Medical Center
OTHER
Canisius-Wilhelmina Hospital
OTHER
Onze Lieve Vrouwe Gasthuis
OTHER
Atrium Medical Center
OTHER
Isala
OTHER
University Medical Center Groningen
OTHER