Non Invasive Mechanical Ventilation Versus Respiratory Rehabilitation in Hypercapnic COPD

PHASE4CompletedINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

March 31, 2006

Primary Completion Date

May 31, 2011

Study Completion Date

May 31, 2011

Conditions
Lung, HyperlucentPositive-Pressure Respiration, Intrinsic
Interventions
PROCEDURE

ventilation

"positive-pressure breathing bilevel (BiPAP ® Respironics, Inc.) Parameters initially programmed be: IPAP 10 cm H2O, EPAP 4 cmH2O, method ST setting yourself respirations 12 breaths minute. The IPAP was progressively increased to a maximum of 20 cm H2O, depending on patient tolerability, clinical response and arterial oxygen saturation was continuously monitored by pulse oximetry, trying to avoid possible leaks through the mask. It can also supply oxygen through a cannula connected to the mask at a flow rate of 2-4 liters per minute to maintain oxygen saturation at around 85-90%.~Patients aired uninterruptedly during nighttime (minimal between 6-8 hours night)."

PROCEDURE

excecise training

"The training program (trained group) was carried out for 12 weeks and sessions of 40 minutes duration:~* 20 minutes of bicycle ergometer with an initial charge of about 70% of initial maximal oxygen consumption, increasing the load every two weeks as tolerated.~* Weightlifting in 2 sets of 6 replicates of 5 simple exercises. These are held at a station multigimnástica (CLASSIC Fitness Center, KETTLER)"

PROCEDURE

Both

both types of intervention

All Listed Sponsors
collaborator

Fondo de Investigacion Sanitaria

OTHER

lead

Hospitales Universitarios Virgen del Rocío

OTHER

NCT01377818 - Non Invasive Mechanical Ventilation Versus Respiratory Rehabilitation in Hypercapnic COPD | Biotech Hunter | Biotech Hunter