NCT01372228View on ClinicalTrials.gov

Phase I/II Pilot Study of Mixed Chimerism to Treat Inherited Metabolic Disorders

PHASE1/PHASE2TerminatedINTERVENTIONAL
Enrollment

3

Participants

Timeline

Start Date

April 30, 2011

Primary Completion Date

April 30, 2016

Study Completion Date

April 30, 2016

Conditions
Hurler Syndrome (MPS I)Hurler-Scheie SyndromeHunter Syndrome (MPS II)Sanfilippo Syndrome (MPS III)Krabbe Disease (Globoid Leukodystrophy)Metachromatic Leukodystrophy (MLD)Adrenoleukodystrophy (ALD and AMN)Sandhoff DiseaseTay Sachs DiseasePelizaeus Merzbacher (PMD)Niemann-Pick DiseaseAlpha-mannosidosis
Interventions
BIOLOGICAL

hematopoietic stem cell infusion

Enriched hematopoetic stem cell infusion

Trial Locations (1)

27705

Duke University Medical Center, Durham

Sponsors

Collaborators (1)

Duke University
All Listed Sponsors
collaborator

Duke University

OTHER

lead

Talaris Therapeutics Inc.

INDUSTRY