NCT01345682 - LUX-Head&Neck 1: A Phase III Trial of Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic (R/M) Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy | Biotech Hunter

Enrollment

483

Participants

Timeline

Start Date

January 5, 2012

Primary Completion Date

March 15, 2014

Study Completion Date

December 6, 2016

Conditions

Head and Neck NeoplasmsCarcinoma, Squamous Cell

Interventions

DRUG

Afatinib

Once daily

DRUG

Methotrexate

Weekly

Trial Locations (101)

4031

1200.43.04101 Boehringer Ingelheim Investigational Site, Basel

63011

1200.43.03306 Boehringer Ingelheim Investigational Site, Clermont-Ferrand

Unknown

1200.43.00113 Boehringer Ingelheim Investigational Site, Harvey

1200.43.00106 Boehringer Ingelheim Investigational Site, Peoria

1200.43.00110 Boehringer Ingelheim Investigational Site, Boston

1200.43.00107 Boehringer Ingelheim Investigational Site, Omaha

1200.43.00105 Boehringer Ingelheim Investigational Site, Stony Brook

1200.43.00102 Boehringer Ingelheim Investigational Site, Philadelphia

1200.43.00103 Boehringer Ingelheim Investigational Site, Philadelphia

1200.43.00109 Boehringer Ingelheim Investigational Site, San Antonio

1200.43.05401 Boehringer Ingelheim Investigational Site, Ciudad Autonoma de Bs As

1200.43.05402 Boehringer Ingelheim Investigational Site, Santa Fe

1200.43.05403 Boehringer Ingelheim Investigational Site, Villa Domínico

1200.43.04303 Boehringer Ingelheim Investigational Site, Leoben

1200.43.04305 Boehringer Ingelheim Investigational Site, Salzburg

1200.43.04301 Boehringer Ingelheim Investigational Site, Vienna

1200.43.03202 Boehringer Ingelheim Investigational Site, Brussels

1200.43.03203 Boehringer Ingelheim Investigational Site, Edegem

1200.43.03204 Boehringer Ingelheim Investigational Site, Ghent

1200.43.03201 Boehringer Ingelheim Investigational Site, Leuven

1200.43.05504 Boehringer Ingelheim Investigational Site, Barretos

1200.43.05505 Boehringer Ingelheim Investigational Site, Jaú

1200.43.05507 Boehringer Ingelheim Investigational Site, Passo Fundo

1200.43.05503 Boehringer Ingelheim Investigational Site, Porto Alegre

1200.43.05502 Boehringer Ingelheim Investigational Site, Rio de Janeiro

1200.43.05501 Boehringer Ingelheim Investigational Site, São Paulo

1200.43.05506 Boehringer Ingelheim Investigational Site, São Paulo

1200.43.04202 Boehringer Ingelheim Investigational Site, Olomouc

1200.43.04201 Boehringer Ingelheim Investigational Site, Prague

1200.43.04203 Boehringer Ingelheim Investigational Site, Prague

1200.43.04501 Boehringer Ingelheim Investigational Site, København Ø

1200.43.03304 Boehringer Ingelheim Investigational Site, Avignon

1200.43.03312 Boehringer Ingelheim Investigational Site, Dijon

1200.43.03303 Boehringer Ingelheim Investigational Site, Lille

1200.43.03301 Boehringer Ingelheim Investigational Site, Lyon

1200.43.03302 Boehringer Ingelheim Investigational Site, Montpellier

1200.43.03307 Boehringer Ingelheim Investigational Site, Nice

1200.43.03314 Boehringer Ingelheim Investigational Site, Paris

1200.43.03305 Boehringer Ingelheim Investigational Site, Poitiers

1200.43.03316 Boehringer Ingelheim Investigational Site, Rouen

1200.43.03309 Boehringer Ingelheim Investigational Site, Saint-Herblain

1200.43.03310 Boehringer Ingelheim Investigational Site, Vandœuvre-lès-Nancy

1200.43.03317 Boehringer Ingelheim Investigational Site, Villejuif

1200.43.04903 Boehringer Ingelheim Investigational Site, Aachen

1200.43.04902 Boehringer Ingelheim Investigational Site, Berlin

1200.43.04909 Boehringer Ingelheim Investigational Site, Dresden

1200.43.04901 Boehringer Ingelheim Investigational Site, Essen

1200.43.04905 Boehringer Ingelheim Investigational Site, Hamburg

1200.43.04906 Boehringer Ingelheim Investigational Site, Hanover

1200.43.04908 Boehringer Ingelheim Investigational Site, Jena

1200.43.04904 Boehringer Ingelheim Investigational Site, Leipzig

1200.43.04907 Boehringer Ingelheim Investigational Site, Mannheim

1200.43.03004 Boehringer Ingelheim Investigational Site, Haidari

1200.43.03005 Boehringer Ingelheim Investigational Site, Heraklion

1200.43.03002 Boehringer Ingelheim Investigational Site, Thessaloniki

1200.43.97201 Boehringer Ingelheim Investigational Site, Haifa

1200.43.97203 Boehringer Ingelheim Investigational Site, Petah Tikva

1200.43.97204 Boehringer Ingelheim Investigational Site, Tel Litwinsky

1200.43.03909 Boehringer Ingelheim Investigational Site, Aosta

1200.43.03908 Boehringer Ingelheim Investigational Site, Cagliari

1200.43.03901 Boehringer Ingelheim Investigational Site, Confreria (CN)

1200.43.03907 Boehringer Ingelheim Investigational Site, Milan

1200.43.03903 Boehringer Ingelheim Investigational Site, Napoli

1200.43.03905 Boehringer Ingelheim Investigational Site, Palermo

1200.43.03902 Boehringer Ingelheim Investigational Site, Savona

1200.43.03904 Boehringer Ingelheim Investigational Site, Taormina (ME)

1200.43.03906 Boehringer Ingelheim Investigational Site, Venezia

1200.43.03910 Boehringer Ingelheim Investigational Site, Viterbo

1200.43.08106 Boehringer Ingelheim Investigational Site, Aichi, Nagoya

1200.43.08103 Boehringer Ingelheim Investigational Site, Chiba, Kashiwa

1200.43.08108 Boehringer Ingelheim Investigational Site, Ehime, Matsuyama

1200.43.08111 Boehringer Ingelheim Investigational Site, Hyogo, Akashi

1200.43.08107 Boehringer Ingelheim Investigational Site, Hyogo, Kobe

1200.43.08109 Boehringer Ingelheim Investigational Site, Kanagawa, Isehara

1200.43.08114 Boehringer Ingelheim Investigational Site, Miyagi, Natori

1200.43.08110 Boehringer Ingelheim Investigational Site, Osaka, Osaka

1200.43.08105 Boehringer Ingelheim Investigational Site, Shizuoka, Sunto-gun

1200.43.08102 Boehringer Ingelheim Investigational Site, Tochigi, Shimotsuke

1200.43.08113 Boehringer Ingelheim Investigational Site, Tokyo, Koto-ku

1200.43.08104 Boehringer Ingelheim Investigational Site, Tokyo, Meguro-ku

1200.43.08112 Boehringer Ingelheim Investigational Site, Tokyo, Minato-ku

1200.43.05202 Boehringer Ingelheim Investigational Site, México

1200.43.00704 Boehringer Ingelheim Investigational Site, Ivanovo

1200.43.00706 Boehringer Ingelheim Investigational Site, Kurski

1200.43.00709 Boehringer Ingelheim Investigational Site, Moscow

1200.43.00703 Boehringer Ingelheim Investigational Site, Omsk

1200.43.00710 Boehringer Ingelheim Investigational Site, Pyatigorsk

1200.43.00707 Boehringer Ingelheim Investigational Site, Saint Petersburg

1200.43.00705 Boehringer Ingelheim Investigational Site, Ufa

1200.43.02703 Boehringer Ingelheim Investigational Site, Cape Town

1200.43.02704 Boehringer Ingelheim Investigational Site, Kraaifontein, Cape Town

1200.43.02701 Boehringer Ingelheim Investigational Site, Parktown, Johannesburg

1200.43.02702 Boehringer Ingelheim Investigational Site, Pretoria

1200.43.03401 Boehringer Ingelheim Investigational Site, Barcelona

1200.43.03404 Boehringer Ingelheim Investigational Site, Barcelona

1200.43.03405 Boehringer Ingelheim Investigational Site, Girona

1200.43.03406 Boehringer Ingelheim Investigational Site, Málaga

1200.43.03402 Boehringer Ingelheim Investigational Site, Salamanca

1200.43.03403 Boehringer Ingelheim Investigational Site, Zaragoza

1200.43.04602 Boehringer Ingelheim Investigational Site, Gothenburg

1200.43.04102 Boehringer Ingelheim Investigational Site, Bern