Mechanisms and Treatment Response of Aggressive Periodontitis in Children

NACompletedINTERVENTIONAL
Enrollment

514

Participants

Timeline

Start Date

December 31, 2006

Primary Completion Date

May 29, 2019

Study Completion Date

December 2, 2022

Conditions
Aggressive Periodontitis
Interventions
PROCEDURE

Diseased periodontal treatment

"Treatment includes scaling and root planing with systemic antibiotics, Amoxicillin 500 mg and Metronidazole 250 mg tid 7 days. At certain intervals after the scaling and root planing, your gums will be reevaluated. You will receive further surgical gum therapy only if your gums haven't shown improvement after first treatment on the reevaluation appointments. If surgery is needed, a bone substituting material may be necessary to fill the spaces where bone has been destroyed by the disease. Extraction of teeth might also be part of gum treatment if the disease is very severe. Re-treatment with antibiotics also may be necessary depending on the response after treatment. You are usually re-examined and receive additional cleanings every 3 to 6 months to ensure the disease does not come back."

PROCEDURE

Conventional periodontal treatment

Scaling and gum measurement will be taken to compare to the treated group.- If it is determined that you do not have this disease, a conventional cleaning is done, usually every 6 months. This is all part of normal clinical care.

Trial Locations (10)

32206

Duval County Department of Health, Jacksonville

32310

Leon County Health Department, Tallahassee

32353

Gadsden County Health Department--Quincy Dental Clinic, Quincy

32610

Dental Clinical Research Unit, University of Florida, Gainesville

32622

Acorn Dental Clinic, Brooker

32640

Azalea Dental Clinic, Gainesville

33013

UF Hialeah Dental Clinic, Hialeah

33301

Broward College, Fort Lauderdale

34113

UF Naples Pediatric Dental Clinic, Naples

40506

University of Kentucky, Lexington

All Listed Sponsors
collaborator

National Institute of Dental and Craniofacial Research (NIDCR)

NIH

lead

University of Florida

OTHER

NCT01330719 - Mechanisms and Treatment Response of Aggressive Periodontitis in Children | Biotech Hunter | Biotech Hunter