Effects of Administration of Fostamatinib on Blood Concentrations of Warfarin in Healthy Subjects

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

March 31, 2011

Primary Completion Date

May 31, 2011

Study Completion Date

May 31, 2011

Conditions

Rheumatoid ArthritisHealthy Subjects

Interventions

DRUG

warfarin

2 single 25 mg doses of Warfarin (5 x 5 mg tablets) administered 14 days apart

DRUG

fostamatinib

2 x 50 mg Fostamatinib tablets (100 mg) twice daily for 13 days

Trial Locations (1)

Research Site, London