Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Total Mesorectal Excision in T2-T3s N0, M0 Rectal Cancer

Capecitabine 825 mg/m2 every 12 hours orally on days of radiotherapy

Radiotherapy was administered in daily fractions of 1.8 Gy 5 days a week according to standard schema. The total dose is 45 Gy plus a boost of 5.4 Gy to the tumor area

6-8 weeks after Chemoradiotherapy

Standard surgical treatment of T2 , T3s, N0, M0 rectal cancer. Early after diagnosis