Analgesic Effect of Different Combinations of Dexketoprofen Trometamol With Tramadol Hydrochloride in a Model of Moderate to Severe Pain

PHASE2CompletedINTERVENTIONAL
Enrollment

745

Participants

Timeline

Start Date

February 28, 2011

Primary Completion Date

October 31, 2011

Study Completion Date

October 31, 2011

Conditions
Pain
Interventions
DRUG

Dexketoprofen Trometamol

Dexketoprofen Trometamol low dose, oral film-coated table, once

DRUG

Dexketoprofen Trometamol

Dexketoprofen Trometamol high dose, oral film-coated table, once

DRUG

Tramadol Hydrochloride

Tramadol Hydrochloride low dose, oral film-coated table, once

DRUG

Tramadol Hydrochloride

Tramadol Hydrochloride high dose, oral film-coated table, once

DRUG

Ibuprofen

Ibuprofen 400 mg, oral film-coated table, once

DRUG

Placebo

Placebo, oral film-coated table, once

DRUG

Dexketoprofen Trometamol + Tramadol Hydrochloride

DKP-TRIS low dose - TRAM.HCl low dose, oral film-coated table, once

DRUG

Dexketoprofen Trometamol + Tramadol Hydrochloride

DKP-TRIS low dose - TRAM.HCl high dose, oral film-coated table, once

DRUG

Dexketoprofen Trometamol + Tramadol Hydrochloride

DKP-TRIS high dose - TRAM.HCl low dose, oral film-coated tablet, once

DRUG

Dexketoprofen Trometamol + Tramadol Hydrochloride

DKP-TRIS high dose - TRAM.HCl high dose, oral film-coated tablet, once

Trial Locations (16)

1052

Dr Tóth Bagi Zoltán Fogászati Rendeloje, Budapest

15706

Hospital Médico Quirúrgico de Conxo, Santiago de Compostela

17475

Klinik und Polickinik für Mund-Kiefer-Gesichtschirurgie/Plastische Operationen Greifswald, Greifswald

24105

Klinik für Mund-, Kiefer- und Gesichtschirurgie, Universitätsklinikum Schleswig Holstein, Campus Kiel, Kiel

28040

Universidad Complutense de Madrid, Madrid

37134

Centro di Ricerche Cliniche di Verona Srl. Policlinico G.B.Rossi, Verona

41009

Departamento de Estomatología, Facultad de Odontología. Universidad de Sevilla, Seville

46014

Hospital General Universitario de Valencia, Valencia

56126

Centro di Farmacologia Clinica per la Sperimentazione dei Farmaci, Pisa

00-852

Gabinet Stomatologiczny Andrzej Wojtowicz AW Clinic, Warsaw

02-791

Dental Service spólka jawna, Warsaw

08907

Facultad de Odontología. Departamento de Cirugía Bucal y Maxilofacial, University of Barcelona - Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet de Llobregat

046010

Departament d'Estomatologia, Clínica Odontològica, Universidad de Valencia - Fundació Lluís Alcanyís, Valencia

B4 6 NN

The School of Dentistry, College of Medical and Dental Sciences, University of Birmingham, Birmingham

M15 6FH

University Dental School Manchester, Manchester

CF14 4 XY

University Dental Hospital, Cardiff

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

PRA Health Sciences

INDUSTRY

lead

Menarini Group

INDUSTRY