349
Participants
Start Date
February 28, 2011
Primary Completion Date
October 31, 2012
Study Completion Date
November 30, 2012
Placebo
"Placebo patches of 2, 4, 6 \& 8 mg / 24 hours Daily application of Placebo patches starting at 2 mg / 24 hours (early Parkinson's Disease (PD) patients) or 4 mg / 24 hours (advanced PD patients). Dose was up-titrated in weekly increments of 2 mg / 24 hours until optimal or maximal dose was reached. Maximal dose was 8 mg / 24 hours for early PD patients and 16 mg / 24 hours for advanced PD patients.~Optimal or maximal dose was maintained for 12 weeks followed by a de-escalation by 2 mg / 24 hours every other day."
Rotigotine
"Rotigotine patches of 2, 4, 6, and 8 mg / 24 hours~Once daily application of Rotigotine patches starting at 2 mg / 24 hours (early Parkinson's Disease (PD) patients) or 4 mg / 24 hours (advanced PD patients). Dose was up-titrated in weekly increments of 2 mg / 24 hours until optimal or maximal dose was reached. Maximal dose is 8 mg / 24 hours for early PD patients and 16 mg / 24 hours for advanced PD patients.~Optimal or maximal dose was maintained for 12 weeks followed by a de-escalation by 2 mg / 24 hours every other day."
101, Feldbach
104, Vienna
107, Vienna
125, Antwerp
121, Bruges
122, Brussels
124, Ghent
131, Liège
44, Plovdiv
52, Rousse
41, Sofia
45, Sofia
48, Sofia
49, Sofia
53, Sofia
42, Varna
232, Chomutov
227, Litomyšl
222, Ostrava-Poruba
231, Pilsen
233, Prague
189, Aix-en-Provence
181, Amiens
186, Limoges
185, Pessac
184, Roanne
183, Toulouse
62, Berlin
77, Berlin
67, Bochum
80, Böblingen
61, Marburg
79, Oldenburg
114, Stuttgart
65, Ulm
73, Westerstede
87, Budapest
88, Budapest
95, Győr
89, Miskolc
81, Nyíregyháza
84, Pécs
86, Szeged
254, Arcugnano
267, Chieti Scalo
270, Napoli
266, Perugia
264, Pisa
257, Pozzilli
262, Roma
269, Treviso
258, Varese
252, Venezia
255, Verona
207, Brasov
201, Bucharest
213, Bucharest
203, Clluj-Napoca
211, Cluj-Napoca
208, Sibiu
217, Sibiu
212, Târgu Mureş
204, Timișoara
209, Timișoara
245, Banská Bystrica
247, Banská Bystrica
240, Bratislava
242, Bratislava
243, Bratislava
249, Dolný Kubín
250, Krompachy
244, Lučenec
248, Žilina
157, Alicante
142, Barcelona
146, Barcelona
143, Madrid
145, Madrid
147, Madrid
148, Madrid
158, Oviedo
141, Sant Cugat (Barcelona)
152, Santiago de Compostela
24, Lugano
21, Sankt Gallen
26, Sargans
22, Zurich
Lead Sponsor
UCB Pharma
INDUSTRY