NCT01288339 - Study Assessing Potential Predictive Tumor Markers in Metastatic Colorectal Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 8, 2010

Primary Completion Date

February 13, 2015

Study Completion Date

February 13, 2015

Conditions

Metastatic Colorectal Cancer

Interventions

DRUG

Panitumumab + FOLFOX (DP)

Panitumumab and FOLFOX will be administered to patients with DP once every 14 days until 6 months of treatment or until disease progression (PD) or unacceptable toxicity. If patients have not progressed after 6 months of treatment with panitumumab and FOLFOX they will continue with panitumumab monotherapy until disease progression.

DRUG

Panitumumab + FOLFOX (no-DP)

Panitumumab and FOLFOX will be administered to patients with no-DP (MMP7+/p-IGF-IR-, MMP7-/p-IGF-IR+ or MMP7-/p-IGF-IR) once every 14 days until 6 months of treatment or until disease progression (PD) or unacceptable toxicity. If patients have not progressed after 6 months of treatment with panitumumab and FOLFOX they will continue with panitumumab monotherapy until disease progression.

Trial Locations (30)

12002

Consorcio Hospitalario Provincial de Castellon, Castellon

13005

Hospital General de Ciudad Real, Ciudad Real

15009

Centro Oncológico de Galícia, A Coruña

17007

Institut Català d'Oncologia (ICO) de Girona, Girona

25198

Hospital Arnau de Vilanova de Lleida, Lleida

26006

Hosptial de Logroño, Logroño

28046

Hospital Universitario La Paz de Madrid, Madrid

28072

Hospital Infanta Sofía de Madrid, Madrid

28222

Hospital Universitario Puerta de Hierro de Madrid, Madrid

28942

Hospital de Fuenlabrada de Madrid, Madrid

30008

Hospital Morales Meseguer, Murcia

31008

Clínica Universitaria de Navarra, Pamplona

Hospital de Navarra, Pamplona

35010

Hosptial Dr. Negrin de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria

36204

Hospital Xeral Cies de Vigo, Vigo

43003

Hosptial de Sant Pau i Santa Tecla de Tarragona, Tarragona

46009

Hospital La Fe de Valencia, Valencia

Instituto Valenciano de Oncología de Valencia, Valencia

46014

Hospital General de Valencia, Valencia

46017

Hospital Dr. Peset de Valencia, Valencia

50009

Hospital Miguel Servet de Zaragoza, Zaragoza

03203

Hospital General Universitario de Elche, Elche

07010

Hospital Son Espases de Mallorca, Palma de Mallorca

07198

Hosptial Son Llatzer de Mallorca, Palma de Mallorca

08906

Hosptial General de l'Hospitalet de Barcelona, L'Hospitalet de Llobregat

08208

Corporació Sanitaria Parc Taulí de Barcelona, Sabadell

08923

Hospital de l'Esperit Sant, Santa Coloma de Gramenet

08036

Hospital Clínic i Provincial de Barcelona, Barcelona

08041

Hospital de la Santa Creu i Sant Pau de Barcelona, Barcelona

09005

Complejo Asitencia de Burgos. Hospital General Yague, Burgos