Metformin in Obese Non-diabetic Pregnant Women

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

450

Participants

Timeline

Start Date

October 31, 2010

Primary Completion Date

July 31, 2015

Study Completion Date

September 30, 2015

Conditions
Pregnancy ComplicationsObesity
Interventions
DRUG

Metformin

Maximum dosage 500 mg 2 tablets 3 times a day (with each meal) start with 1 tablet twice a day and gradually titrate upwards to maximum dose

DRUG

Placebo

Placebo maximum dosage 2 tablets 3 times a day ( with meals) start with 1 tablet twice a day and gradually titrate upwards to maximum dose

Trial Locations (3)

ME7 5NY

Medway Hospital NHS Trust, Gillingham

SM5 1AA

Epsom and St Helier University Hospitals NHS Trust, Carshalton

SE5 8RX

Kings College, London, London

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Fetal Medicine Foundation

OTHER

collaborator

King's College Hospital NHS Trust

OTHER

lead

Epsom and St Helier University Hospitals NHS Trust

OTHER