NCT01272219View on ClinicalTrials.gov

Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: SCALE™ - Obesity and Pre-diabetes

PHASE3CompletedINTERVENTIONAL
Enrollment

3,731

Participants

Timeline

Start Date

June 1, 2011

Primary Completion Date

March 18, 2013

Study Completion Date

March 2, 2015

Conditions
Metabolism and Nutrition DisorderObesity
Interventions
DRUG

liraglutide

Subject with no pre-diabetes at screening, receiving liraglutide 3.0 mg subcutaneous (under the skin) injection once daily for 56 weeks. Subjects completing 56 weeks are re-randomised to receive liraglutide 3.0 mg for 12 weeks (until week 68).

DRUG

placebo

Subject with no pre-diabetes at screening, receiving liraglutide 3.0 mg subcutaneous (under the skin) injection once daily for 56 weeks. Subjects completing 56 weeks are re-randomised to receive liraglutide placebo for 12 weeks (until week 68).

DRUG

liraglutide

Liraglutide 3.0 mg, subcutaneous (under the skin) injection once daily for 160 weeks.

DRUG

placebo

Liraglutide placebo, subcutaneous (under the skin) injection once daily for 160 weeks.

Trial Locations (226)

1090

Novo Nordisk Investigational Site, Vienna

1130

Novo Nordisk Investigational Site, Vienna

1211

Novo Nordisk Investigational Site, Geneva

1958

Novo Nordisk Investigational Site, Frederiksberg C

2006

Novo Nordisk Investigational Site, University of Sydney

2193

Novo Nordisk Investigational Site, Johannesburg

2650

Novo Nordisk Investigational Site, Edegem

Novo Nordisk Investigational Site, Hvidovre

3010

Novo Nordisk Investigational Site, Bern

3081

Novo Nordisk Investigational Site, Heidelberg West

3117

Novo Nordisk Investigational Site, Tønsberg

4000

Novo Nordisk Investigational Site, Liège

4102

Novo Nordisk Investigational Site, Woolloongabba

5005

Novo Nordisk Investigational Site, Adelaide

5020

Novo Nordisk Investigational Site, Salzburg

5405

Novo Nordisk Investigational Site, Dättwil

7030

Novo Nordisk Investigational Site, Trondheim

7130

Novo Nordisk Investigational Site, Cape Town

7300

Novo Nordisk Investigational Site, Boussu

8000

Novo Nordisk Investigational Site, Århus C

8036

Novo Nordisk Investigational Site, Graz

8125

Novo Nordisk Investigational Site, Zollikerberg

9016

Novo Nordisk Investigational Site, Sankt Gallen

10025

Novo Nordisk Investigational Site, New York

10301

Novo Nordisk Investigational Site, Staten Island

11000

Novo Nordisk Investigational Site, Belgrade

Novo Nordisk Investigational Site, Belgrade

13055

Novo Nordisk Investigational Site, Berlin

13210

Novo Nordisk Investigational Site, Syracuse

14000

Novo Nordisk Investigational Site, Mexico City

14609

Novo Nordisk Investigational Site, Rochester

15009

Novo Nordisk Investigational Site, Beaver

15206

Novo Nordisk Investigational Site, Pittsburgh

15706

Novo Nordisk Investigational Site, Santiago de Compostela

19107

Novo Nordisk Investigational Site, Philadelphia

19611

Novo Nordisk Investigational Site, West Reading

20145

Novo Nordisk Investigational Site, Milan

21209

Novo Nordisk Investigational Site, Baltimore

22206

Novo Nordisk Investigational Site, Arlington

23233

Novo Nordisk Investigational Site, Henrico

23294

Novo Nordisk Investigational Site, Richmond

23454

Novo Nordisk Investigational Site, Virginia Beach

27518

Novo Nordisk Investigational Site, Cary

27612

Novo Nordisk Investigational Site, Raleigh

28006

Novo Nordisk Investigational Site, Madrid

29425

Novo Nordisk Investigational Site, Charleston

29651

Novo Nordisk Investigational Site, Greer

30024

Novo Nordisk Investigational Site, Suwanee

30328

Novo Nordisk Investigational Site, Sandy Springs

30338

Novo Nordisk Investigational Site, Dunwoody

30606

Novo Nordisk Investigational Site, Athens

31096

Novo Nordisk Investigational Site, Haifa

32081

Novo Nordisk Investigational Site, Ponte Vedra

32117

Novo Nordisk Investigational Site, Daytona Beach

32205

Novo Nordisk Investigational Site, Jacksonville

32216

Novo Nordisk Investigational Site, Jacksonville

33143

Novo Nordisk Investigational Site, South Miami

33437

Novo Nordisk Investigational Site, Boynton Beach

34000

Novo Nordisk Investigational Site, Durango

34098

Novo Nordisk Investigational Site, Istanbul

34201

Novo Nordisk Investigational Site, Bradenton

34371

Novo Nordisk Investigational Site, Istanbul

34429

Novo Nordisk Investigational Site, Crystal River

34471

Novo Nordisk Investigational Site, Ocala

34668

Novo Nordisk Investigational Site, Istanbul

34760

Novo Nordisk Investigational Site, Istanbul

35128

Novo Nordisk Investigational Site, Padua

35392

Novo Nordisk Investigational Site, Giessen

38518

Novo Nordisk Investigational Site, Gifhorn

40138

Novo Nordisk Investigational Site, Bologna

41003

Novo Nordisk Investigational Site, Seville

42084

Novo Nordisk Investigational Site, Pachuca

44281

Novo Nordisk Investigational Site, Kfar Saba

44600

Novo Nordisk Investigational Site, Guadalajara

44614

Novo Nordisk Investigational Site, Canal Fulton

44650

Novo Nordisk Investigational Site, Guadalajara

44800

Novo Nordisk Investigational Site, Saint-Herblain

45005

Novo Nordisk Investigational Site, Franklin

45219

Novo Nordisk Investigational Site, Cincinnati

47005

Novo Nordisk Investigational Site, Valladolid

47051

Novo Nordisk Investigational Site, Duisburg

49100

Novo Nordisk Investigational Site, Petah Tikva

49372

Novo Nordisk Investigational Site, Petah Tikva

50139

Novo Nordisk Investigational Site, Florence

52621

Novo Nordisk Investigational Site, Tel Litwinsky

53100

Novo Nordisk Investigational Site, Siena

53209

Novo Nordisk Investigational Site, Milwaukee

56124

Novo Nordisk Investigational Site, Pisa

59037

Novo Nordisk Investigational Site, Lille

60504

Novo Nordisk Investigational Site, Aurora

61231

Novo Nordisk Investigational Site, Bad Nauheim

63104

Novo Nordisk Investigational Site, St Louis

63141

Novo Nordisk Investigational Site, St Louis

63376

Novo Nordisk Investigational Site, City of Saint Peters

64111

Novo Nordisk Investigational Site, Kansas City

64239

Novo Nordisk Investigational Site, Tel Aviv

64700

Novo Nordisk Investigational Site, Monterrey

66386

Novo Nordisk Investigational Site, Saint Ingbert

66606

Novo Nordisk Investigational Site, Topeka

68163

Novo Nordisk Investigational Site, Mannheim

69495

Novo Nordisk Investigational Site, Pierre-Bénite

74136

Novo Nordisk Investigational Site, Tulsa

75231

Novo Nordisk Investigational Site, Dallas

75234

Novo Nordisk Investigational Site, Dallas

75251

Novo Nordisk Investigational Site, Dallas

75651

Novo Nordisk Investigational Site, Paris

75877

Novo Nordisk Investigational Site, Paris

77479

Novo Nordisk Investigational Site, Sugar Land

78731

Novo Nordisk Investigational Site, Austin

79106

Novo Nordisk Investigational Site, Freiburg im Breisgau

80045

Novo Nordisk Investigational Site, Aurora

80401

Novo Nordisk Investigational Site, Golden

80904

Novo Nordisk Investigational Site, Colorado Springs

84107

Novo Nordisk Investigational Site, Salt Lake City

85027

Novo Nordisk Investigational Site, Phoenix

87520

Novo Nordisk Investigational Site, Ofakim

89000

Novo Nordisk Investigational Site, Tampico

90127

Novo Nordisk Investigational Site, Palermo

90220

Novo Nordisk Investigational Site, Oulu

90404

Novo Nordisk Investigational Site, Santa Monica

91120

Novo Nordisk Investigational Site, Jerusalem

92037

Novo Nordisk Investigational Site, La Jolla

92108

Novo Nordisk Investigational Site, San Diego

92646

Novo Nordisk Investigational Site, Huntington Beach

92801

Novo Nordisk Investigational Site, Anaheim

94520

Novo Nordisk Investigational Site, Concord

97401

Novo Nordisk Investigational Site, Eugene

98057

Novo Nordisk Investigational Site, Renton

101990

Novo Nordisk Investigational Site, Moscow

115093

Novo Nordisk Investigational Site, Moscow

117036

Novo Nordisk Investigational Site, Moscow

121356

Novo Nordisk Investigational Site, Moscow

125367

Novo Nordisk Investigational Site, Moscow

127486

Novo Nordisk Investigational Site, Moscow

132001

Novo Nordisk Investigational Site, Karnāl

163045

Novo Nordisk Investigational Site, Arkhangelsk

400007

Novo Nordisk Investigational Site, Mumbai

400703

Novo Nordisk Investigational Site, Mumbai

411030

Novo Nordisk Investigational Site, Pune

590001

Novo Nordisk Investigational Site, Belagavi

620018

Novo Nordisk Investigational Site, Trichy

625023

Novo Nordisk Investigational Site, Tyumen

630047

Novo Nordisk Investigational Site, Novosibirsk

682026

Novo Nordisk Investigational Site, Kerala

4000021

Novo Nordisk Investigational Site, Mumbai

35205-4731

Novo Nordisk Investigational Site, Birmingham

92103-4140

Novo Nordisk Investigational Site, San Diego

06320

Novo Nordisk Investigational Site, New London

06708

Novo Nordisk Investigational Site, Waterbury

20036-5847

Novo Nordisk Investigational Site, Washington D.C.

70808-4124

Novo Nordisk Investigational Site, Baton Rouge

21075-6437

Novo Nordisk Investigational Site, Elkridge

02747

Novo Nordisk Investigational Site, North Dartmouth

44281-9236

Novo Nordisk Investigational Site, Wadsworth

37620-7352

Novo Nordisk Investigational Site, Bristol

75390-8858

Novo Nordisk Investigational Site, Dallas

78229-4801

Novo Nordisk Investigational Site, San Antonio

84088-8871

Novo Nordisk Investigational Site, West Jordan

98801-2028

Novo Nordisk Investigational Site, Wenatchee

C1426ABP

Novo Nordisk Investigational Site, Ciudad Autónoma de Bs As

C1406FWY

Novo Nordisk Investigational Site, Ciudad Autónoma de BsAs

C1405CWB

Novo Nordisk Investigational Site, Ciudad de Buenos Aires

B7600FZN

Novo Nordisk Investigational Site, Mar del Plata

90035-170

Novo Nordisk Investigational Site, Porto Alegre

13073-350

Novo Nordisk Investigational Site, Campinas

05403-000

Novo Nordisk Investigational Site, São Paulo

80030-110

Novo Nordisk Investigational Site, Curitiba

04022-002

Novo Nordisk Investigational Site, São Paulo

T2T 5C7

Novo Nordisk Investigational Site, Calgary

T6G 2E1

Novo Nordisk Investigational Site, Edmonton

A1N 1W7

Novo Nordisk Investigational Site, Mount Pearl

A1A 3R5

Novo Nordisk Investigational Site, St. John's

B3H 2Y9

Novo Nordisk Investigational Site, Halifax

N1R 7L6

Novo Nordisk Investigational Site, Cambridge

L8L 2X2

Novo Nordisk Investigational Site, Hamilton

L8M 1K7

Novo Nordisk Investigational Site, Hamilton

K1H 1A2

Novo Nordisk Investigational Site, Ottawa

H9R 4S3

Novo Nordisk Investigational Site, Pointe-Claire

G1V 4G2

Novo Nordisk Investigational Site, Québec

G1V 4G5

Novo Nordisk Investigational Site, Québec

07100

Novo Nordisk Investigational Site, Kuopio

00014

Novo Nordisk Investigational Site, University of Helsinki

06600

Novo Nordisk Investigational Site, Antibes

01219

Novo Nordisk Investigational Site, Dresden

04103

Novo Nordisk Investigational Site, Leipzig

Unknown

Novo Nordisk Investigational Site, Shatin, New Territories

Novo Nordisk Investigational Site, Dublin

H-1115

Novo Nordisk Investigational Site, Budapest

H-1134

Novo Nordisk Investigational Site, Budapest

H-4012

Novo Nordisk Investigational Site, Debrecen

560 017

Novo Nordisk Investigational Site, Bangalore

DUBLIN 4

Novo Nordisk Investigational Site, Dublin

DUBLIN 8

Novo Nordisk Investigational Site, Dublin

H91 YR71

Novo Nordisk Investigational Site, Galway

00168

Novo Nordisk Investigational Site, Roma

03300

Novo Nordisk Investigational Site, Mexico City

1311RL

Novo Nordisk Investigational Site, Almere Stad

1066 EC

Novo Nordisk Investigational Site, Amsterdam

6191JW

Novo Nordisk Investigational Site, Beek

7555 DL

Novo Nordisk Investigational Site, Hengelo OV

1213 RH

Novo Nordisk Investigational Site, Hilversum

2262 BA

Novo Nordisk Investigational Site, Leidschendam

3331 LZ

Novo Nordisk Investigational Site, Zwijndrecht

NO-5012

Novo Nordisk Investigational Site, Bergen

0424

Novo Nordisk Investigational Site, Oslo

15-381

Novo Nordisk Investigational Site, Bialystok

40-662

Novo Nordisk Investigational Site, Katowice

40-767

Novo Nordisk Investigational Site, Katowice

60-569

Novo Nordisk Investigational Site, Poznan

70-483

Novo Nordisk Investigational Site, Szczecin

71-455

Novo Nordisk Investigational Site, Szczecin

02-507

Novo Nordisk Investigational Site, Warsaw

0083

Novo Nordisk Investigational Site, Pretoria

04001

Novo Nordisk Investigational Site, Almería

08036

Novo Nordisk Investigational Site, Barcelona

06100

Novo Nordisk Investigational Site, Ankara

06110

Novo Nordisk Investigational Site, Ankara

CV2 2DX

Novo Nordisk Investigational Site, Coventry

G11 6NT

Novo Nordisk Investigational Site, Glasgow

HU3 2RW

Novo Nordisk Investigational Site, Hull

L9 7AL

Novo Nordisk Investigational Site, Liverpool

SE1 9RT

Novo Nordisk Investigational Site, London

W1T 7DN

Novo Nordisk Investigational Site, London

W6 8RF

Novo Nordisk Investigational Site, London

LU4 0DZ

Novo Nordisk Investigational Site, Luton

SA6 6NL

Novo Nordisk Investigational Site, Swansea

Sponsors

Lead Sponsor

Novo Nordisk A/S
All Listed Sponsors
lead

Novo Nordisk A/S

INDUSTRY

NCT01272219 - Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: SCALE™ - Obesity and Pre-diabetes | Biotech Hunter | Biotech Hunter