Study of Epratuzumab Versus Placebo in Subjects With Moderate to Severe General Systemic Lupus Erythematosus (SLE)

PHASE3CompletedINTERVENTIONAL
Enrollment

791

Participants

Timeline

Start Date

December 31, 2010

Primary Completion Date

May 31, 2015

Study Completion Date

June 30, 2015

Conditions
Systemic Lupus Erythematosus
Interventions
DRUG

Placebo

Placebo infusions delivered weekly for 4 weeks over four 12-week treatment cycles

DRUG

Epratuzumab

600 mg infusions delivered weekly for a total of 4 weeks (cumulative dose 2400 mg) over four 12- week treatment cycles

DRUG

Epratuzumab

1200 mg infusions delivered every other week for a total of 4 weeks (cumulative dose 2400 mg) over four 12-week treatment cycles

Trial Locations (133)

Unknown

539, Birmingham

557, Little Rock

515, Hemet

544, Huntington Beach

550, La Jolla

548, Los Angeles

589, San Diego

531, San Leandro

558, Torrance

594, Westlake Village

532, Denver

511, Bridgeport

514, Brandon

533, Fort Lauderdale

518, Plantation

585, Port Orange

538, Tampa

537, Atlanta

587, Decatur

590, Idaho Falls

543, Bowling Green

592, Lexington

576, New Orleans

572, Boston

554, Ann Arbor

513, Lansing

599, Lansing

575, Florissant

549, St Louis

596, Nashua

593, Clifton

568, Freehold

551, Brooklyn

553, Lake Success

545, Manhasset

577, Roslyn

559, Charlotte

547, Tulsa

561, Wyomissing

535, Charleston

598, Myrtle Beach

571, Jackson

574, Amarillo

570, Austin

541, Houston

563, Houston

562, San Antonio

552, Chesapeake

534, Seattle

954, Belo Horizonte

956, Campinas

955, Goiânia

950, Juiz de Fora

952, Rio de Janeiro

506, St. John's

507, Mississauga

508, Rimouski

502, Hamilton

500, London

504, Toronto

517, Victoria

613, Caen

618, Limoges

617, Montpellier

614, Paris

616, Toulouse

628, Berlin

633, Berlin

625, Cologne

636, Dessau

637, Hamburg

632, Herne

629, Kiel

626, Leipzig

634, Mainz

627, Münster

639, Wiesbaden

631, Zerbst

712, Budapest

716, Budapest

718, Budapest

717, Debrecen

711, Szeged

715, Szeged

713, Zalaegerszeg

852, Ahmedabad

853, Bangalore

648, Milan

647, Pisa

646, Roma

978, Cuauhtémoc

976, Mexico City

982, México

981, Torreón

743, Bydgoszcz

744, Częstochowa

752, Elblag

745, Katowice

746, Katowice

748, Lublin

750, Lublin

742, Poznan

747, Szczecin

751, Ustroń

749, Warsaw

757, Bucharest

758, Bucharest

760, Bucharest

759, Constanța

756, Galati

761, Iași

778, Kemerovo

780, Kemerovo

779, Moscow

901, Cape Town

902, Durban

903, Stellenbosch

661, Barcelona

660, Getafe

662, Las Palmas de Gran Canaria

664, Madrid

663, Santiago de Compostela

659, Vigo

791, Donetsk

790, Kiev

794, Kiev

797, Kiev

792, Luhansk

793, Odesa

796, Vinnytsia

677, Birmingham

678, Christchurch

679, London

Sponsors

Lead Sponsor

All Listed Sponsors
lead

UCB Pharma

INDUSTRY