Effect Of Rifampin On Pharmacokinetics Of Sitaxsentan

PHASE1WithdrawnINTERVENTIONAL

Timeline

Start Date

December 31, 2010

Primary Completion Date

January 31, 2011

Study Completion Date

January 31, 2011

Conditions

Pulmonary Arterial Hypertension

Interventions

DRUG

Sitaxsentan alone

Days 1-5: Sitaxsentan tablet, 100 mg, q24 h (once a day)

DRUG

Sitaxsentan

Days 6-12: Sitaxsentan tablet, 100 mg, q24h (once a day)

DRUG

Rifampin

Days 6-12: Rifampin capsule, 600 mg, q24h (once a day)