Raltegravir Switch Study to Reduce Liver Fibrosis Progression in HIV-Hepatitis C Co-infection

PHASE2CompletedINTERVENTIONAL
Enrollment

9

Participants

Timeline

Start Date

December 31, 2011

Primary Completion Date

March 31, 2016

Study Completion Date

September 30, 2016

Conditions
HIVHepatitis CLiver Fibrosis
Interventions
DRUG

Raltegravir

Subjects will maintain their nucleoside backbone and switch ritonavir-boosted protease inhibitor to Raltegravir 400 mg po BID for 48 weeks.

DRUG

Ritonavir-boosted protease inhibitor

Subjects will maintain their nucleoside backbone and remain on a ritonavir-boosted protease inhibitor at standard doses for for 48 weeks

Trial Locations (3)

V6Z 1Y6

Providence Health Care- St. Paul's Hospital, Vancouver

M5G2N2

University Health Network - Toronto General Hospital Division, Toronto

Unknown

Montreal Chest Institute, Montreal

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

collaborator

CIHR Canadian HIV Trials Network

NETWORK

lead

McGill University Health Centre/Research Institute of the McGill University Health Centre

OTHER

NCT01231685 - Raltegravir Switch Study to Reduce Liver Fibrosis Progression in HIV-Hepatitis C Co-infection | Biotech Hunter | Biotech Hunter