Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's Lymphoma

PHASE3CompletedINTERVENTIONAL
Enrollment

573

Participants

Timeline

Start Date

June 30, 1996

Primary Completion Date

September 30, 2001

Study Completion Date

October 31, 2004

Conditions
Cardiac ToxicityLeukemiaLymphoma
Interventions
DRUG

asparaginase

Given IV

DRUG

cytarabine

Given IV

DRUG

dexrazoxane hydrochloride

Given IV

DRUG

doxorubicin hydrochloride

Given IV

DRUG

leucovorin calcium

Given IV

DRUG

mercaptopurine

Given orally

DRUG

methotrexate

Given IV

DRUG

prednisone

Given orally

DRUG

therapeutic hydrocortisone

Given IT

DRUG

vincristine sulfate

Given IV

RADIATION

radiation therapy

Radiation to cranium

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Children's Oncology Group

NETWORK

NCT01230983 - Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's Lymphoma | Biotech Hunter | Biotech Hunter