NCT01230580View on ClinicalTrials.gov

Protease Inhibitor Monotherapy Versus Ongoing Triple-therapy in the Long Term Management of HIV Infection (PIVOT)

PHASE4UnknownINTERVENTIONAL
Enrollment

587

Participants

Timeline

Start Date

November 30, 2008

Primary Completion Date

November 30, 2013

Study Completion Date

November 30, 2013

Conditions
HIV InfectionAcquired Immunodeficiency Syndrome
Interventions
DRUG

Protease Inhibitor

Switch to a regimen comprising a single ritonavir-boosted Protease Inhibitor

DRUG

Standard-of-care Antiretroviral therapy

Regimen should consist of 3 drugs: 2 nucleoside reverse transcriptase inhibitors with either a non-nucleoside reverse transcriptase inhibitor or a protease inhibitor

Sponsors
All Listed Sponsors
collaborator

NHS Health Technology Assessment Programme

OTHER

lead

Medical Research Council

OTHER_GOV