Amyloid Imaging And Safety Study Of ACC-001 In Subjects With Early Alzheimer's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

February 28, 2011

Primary Completion Date

February 28, 2014

Study Completion Date

February 28, 2014

Conditions
Alzheimer's Disease
Interventions
BIOLOGICAL

ACC-001 3 μg/ QS-21 50 μg

ACC-001 3 μg/ QS-21 50 μg IM on day 1, month 1, month 3, month 6, month 12, and month 18

BIOLOGICAL

ACC-001 10 μg/ QS-21 50 μg

ACC-001 10 μg/ QS-21 50 μg IM on day 1, month 1, month 3, month 6, month 12, and month 18

OTHER

Placebo- Phosphate buffered saline (PBS)

Phosphate buffered saline IM on day 1, month 1, month 3, month 6, month 12, and month 18

Trial Locations (40)

12065

Satatoga PET Associates, Clifton Park

20007

Clinical Research Unit, Washington D.C.

Georgetown University Hospital, Washington D.C.

20057

Georgetown University Medical Center Department of Neurology, Washington D.C.

33137

Miami Jewish Health Systems, Miami

33140

Mount Sinai Medical Center, Miami Beach

33407

Premiere Research Institute (Palm Beach Neurology), West Palm Beach

33907

Florida Neurology Group PL, Fort Myers

33912

Internal Medicine Associates of Lee County, MD, PA, Fort Myers

Neuropsychiatric Research Center of Southwest Florida, Fort Myers

33919

Florida Radiology Leasing, Limited Liability Corporation, Fort Myers

Radiology Regional Center, Fort Myers

34601

Meridien Research, Brooksville

68105

University of Nebraska Medical Center, Omaha

77030

Baylor College of Medicine, Department of Neurology, Houston

85006

Banner Alzheimer's Institute, Phoenix

Banner Good Samaritan Medical Center, Phoenix

85351

Banner Boswell Medical Center, Sun City

Banner Lakes Imaging Center, Sun City

Banner Sun Health Research Institute, Sun City

85719

Southwest PET Institute, Tucson

85724

Universal Medical Center, Tucson

85741

Northwest NeuroSpecialists, LLC, Tucson

Radiology Limited, Tucson

89106

Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas

89128

Steinberg Diagnostic Imaging, Las Vegas

89135

Nevada Cancer Institute, Las Vegas

93030

Pacific Neuroscience Medical Group, Oxnard

85724-5023

University of Arizona, Health Sciences Center - Department of Neurology, Tucson

06510

GCRC (Drug administered), New Haven

Yale University School of Medicine, Alzheimer's Disease Research Unit, New Haven

06511

Investigational Drug Service, New Haven

06519

Norman S. Werdiger, MD, New Haven

02114

Massachusetts General Hospital (For PET only), Boston

02115

Brigham and Women's Hospital, Boston

07724

Memory Enhancement Center of America, Incorporated, Eatontown

02914

Rhode Island Mood and Memory Research Institute, East Providence

02906

Butler Hospital, Providence

05201

The Memory Clinic, Bennington

The Pharmacy Inc., Bennington

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

JANSSEN Alzheimer Immunotherapy Research & Development, LLC

INDUSTRY

lead

Pfizer

INDUSTRY