Fixed Versus Flexible Dosing of Pregabalin in Patients With Fibromyalgia

PHASE4CompletedINTERVENTIONAL
Enrollment

174

Participants

Timeline

Start Date

July 31, 2010

Primary Completion Date

July 31, 2012

Study Completion Date

July 31, 2012

Conditions
Fibromyalgia
Interventions
DRUG

Pregabalin

"Fixed dosing of pregabalin: Week 1: 75 mg bid. Weeks 2 - 8: 150 mg bid. Week 9 (Days 57-60 and Days 61-63): 75 mg bid.~Flexible dosing of pregabalin: Week 1: placebo in the AM and 75 mg nightly; Week 2: placebo in the AM and 150 mg nightly.; Week 3 placebo in the a.m., 225 mg nightly; Weeks 4 - 8 placebo in the a.m., 300 mg nightly. Week 9 (Days 57-60) placebo in the a.m,, 150 mg bid nightly and Days 61-63: placebo in the a.m., and 75 mg bid nightly."

Trial Locations (5)

85704

Catalina Pointe Clinial Research, Tucson

90211

David Silver MD Inc, Beverly Hills

Stuart L Silverman MD Inc., Beverly Hills

91307

Affilaites in Medical Specialty, West Hills

92646

Talbert Medical Group, Huntington Beach

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pfizer

INDUSTRY

lead

Osteoporosis Medical Center, Beverly Hills, CA

OTHER