Vaccine Therapy, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

PHASE1CompletedINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

July 31, 2010

Primary Completion Date

February 28, 2015

Study Completion Date

February 28, 2015

Conditions
Brain and Central Nervous System Tumors
Interventions
BIOLOGICAL

glioblastoma multiforme multipeptide vaccine IMA950

BIOLOGICAL

sargramostim

DRUG

temozolomide

OTHER

laboratory biomarker analysis

OTHER

pharmacological study

PROCEDURE

adjuvant therapy

RADIATION

radiation therapy

Trial Locations (7)

CB2 2QQ

Addenbrooke's Hospital, Cambridge

WC1E 6DD

UCL Cancer Institute, London

SO16 6YD

Southampton General Hospital, Southampton

G12 0YN

Beatson West of Scotland Cancer Centre, Glasgow

EH4 2XU

Western General Hospital, Edinburgh

LS9 7TF

St James' University Hospital, Leeds

M20 4BX

The Christie NHS Foundation Trust, Manchester

Sponsors
All Listed Sponsors
collaborator

Immatics Biotechnologies GmbH

INDUSTRY

lead

Cancer Research UK

OTHER