Evaluation of Succinate Metoprolol on Heart Rate in the Stable Angina Patients

PHASE4CompletedINTERVENTIONAL
Enrollment

251

Participants

Timeline

Start Date

October 31, 2010

Primary Completion Date

September 30, 2011

Study Completion Date

September 30, 2011

Conditions
Angina Pectoris
Interventions
DRUG

Succinate Metoprolol (Betaloc ZOK®)

treatment with 47.5mg for two weeks, if tolerated and without Systolic blood pressure\<100mmHg and heart rate \<45 bpm according to 12-lead Electrocardiogram at Week 3, the dosage will be titrated to 95mg and last for another 6 weeks

DRUG

Succinate Metoprolol (Betaloc ZOK®)

Treatment with 95mg for two weeks, and if tolerated and without bradycardia symptoms presented, Systolic blood pressure\<100mmHg and heart rate \<45 bpm according to 12-lead Electrocardiogram at Week 3,the dosage will be force titrated to 190mg and last for another 6 weeks

Trial Locations (10)

Unknown

Research Site, Beijing

Research Site, Guangzhou

Research Site, Tangshan

Research Site, Zhengzhou

Research Site, Nanjing

Research Site, Jingzhou

Research Site, Shenyang

Research Site, Shanghai

Research Site, Taiyuan

Research Site, Tianjing

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY