30
Participants
Start Date
October 31, 2010
Primary Completion Date
April 30, 2011
Study Completion Date
April 30, 2011
GLPG0259 oral capsule
Two capsules, each containing 25 mg of GLPG0259 (i.e. 50 mg/day), to be given once daily; in case of adverse events the dose may be split over two administrations, or reduced to 25 mg/day (one single capsule)
Placebo
Placebo capsules; two capsules to be taken in the morning, in case of adverse events the dose may be split over two administrations, or reduced to one single capsule
GLPG0259 (Part B)
Capsule, dosage to be established based on results of Part A
Placebo (Part B)
Capsules, dosage to be established after Part A, and matching GLPG0259 (Part B)
Cliniques Universitaires Saint-Luc, Brussels
KU Leuven, Leuven
AZ Alma, Sijsele-Damme
Vinnytsia Regional Hospital, Vinnytsia
Chernivtsi Regional Clinical Hospital, Chernivtsi
Kharkiv City Clinical Hospital No.27, Kharkiv
Kharkiv City Clinical Hospital No.8, Kharkiv
Zaporizhzhia Regional Hospital, Zaporizhzhya
Donetsk City Hospital No5, Donetsk
University Clinic, Crimean Medical University, Simferopol
"State Educational Institution of Higher Professional Education Moscow State Medico-Stomatological University of Roszdrav State Healthcare Institution of City Moscow City Clinical Ordena Trudovogo Krasnogo Znameny Hospital #23 n.a. Medsantrud", Moscow
"State Healthcare Institution of city Moscow City Clinical Ordena Trudovogo Krasnogo Znameny Hospital #23 n.a. Medsantrud", Moscow
"State Educational Institution of Higher Professional Education Russian State Medical University of Roszdrav State Healthcare Institution of City Moscow City Clinical Hospital #15 n.a. O.M. Filatov", Moscow
"State Healthcare Institution of City Moscow City Clinical Hospital #4", Moscow
"State Healthcare Institution of City Moscow City Clinical Hospital #7", Moscow
Institution Russian Academy of Medical Sciences Scientific Research Institution of Rheumatology RAMN, Moscow
"State Healthcare Institution of City Moscow City Clinical Hospital #1 n.a. Pirogov", Moscow
"Saint-Petersburg State Healthcare Institution City Pokrovskaya Hospital", Saint Petersburg
"State Educational Institution of Higher Professional Education Moscow State Medico-Stomatological University of Roszdrav at the State Healthcare Institution of city Moscow City Clinical Ordena Trudovogo Krasnogo Znameny hospital #23 n.a. M", Moscow
"Saint-Petersburg State Healthcare Institution City Mariinskiy Hospital", Saint Petersburg
Institution of Russian Academy of Sciences Saint-Petersburg Clinical Hospital RAN, Saint Petersburg
"State Educational Institution of Higher Professional Education Saint-Petersburg State Pediatric Medical Academy of Roszdrav", Saint Petersburg
"Saint-Petersburg State Healthcare Institution City Hospital #26", Moscow
UMC Leiden, Leiden
Specjalistyczne Centrum Medyczne NZOZ NOWOMED, Krakow
"Linea Corporis - Chirurgia Plastyczna Sp. z o.o.", Warsaw
Mokotowskie Centrum Osteoporozy S.C., Warsaw
Synexus SCM Sp. z o.o., Wroclaw
Akademia Medyczna im. Piastów Śląskich we Wroclawiu Katedra i Klinika Reumatologii i Chorób Wewnętrznych UM we Wrocławiu, Wroclaw
Kyiv City Clinical Hospital No.3, Kyiv
Central Pool-type Clinical Hospital MoH of Ukraine, Kyiv
Institute of Gerontology AMS of Ukraine, Kyiv
Lead Sponsor
Galapagos NV
INDUSTRY