The Correlation of COX-2 Expression in Human Polymorphonuclear Leukocytes/Macrophages (PMNL/MP) and Postoperative Pain

PHASE4CompletedINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

November 30, 2010

Primary Completion Date

June 30, 2011

Study Completion Date

September 30, 2011

Conditions
Post-Operative Pain
Interventions
DRUG

Parecoxib Sodium

40 mg Parecoxib Sodium is give to the patients intravenously (diluted with 5 ml normal saline) at 30 minutes before surgery, 20 mg Parecoxib Sodium (diluted with 5 ml normal saline) at 8 hours,20 hours,32 hours,44 hours,56 hours after surgery respectively.

Trial Locations (1)

430030

Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pfizer

INDUSTRY

lead

Xianwei Zhang

OTHER