NCT01177813View on ClinicalTrials.gov

Efficacy and Safety of Empagliflozin (BI 10773) Versus Placebo and Sitagliptin Over 24 Weeks in Patients With Type 2 Diabetes

PHASE3CompletedINTERVENTIONAL
Enrollment

986

Participants

Timeline

Start Date

July 31, 2010

Primary Completion Date

March 31, 2012

Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG

Placebo identical to BI10773 high dose

placebo tablets once daily

DRUG

BI 10773

BI 10773 low dose tablet once daily

DRUG

BI 10773 open label

Patients receive BI 10773 high dose tablets open label once daily

DRUG

Placebo identical to BI10773 low dose

placebo tablets once daily

DRUG

Placebo identical to BI10773 low dose

placebo tablets once daily

DRUG

Placebo identical to BI10773 high dose

placebo tablets once daily

DRUG

Placebo identical to Sitagliptin 100mg

placebo tablets once daily

DRUG

Placebo identical to Sitagliptin 100mg

placebo tablets once daily

DRUG

BI10773

BI 10773 high dose tablets once daily

DRUG

Sitagliptin

Sitagliptin tablets 100 mg once daily

DRUG

Placebo identical to Sitagliptin 100mg

placebo tablets once daily

DRUG

Placebo identical to BI10773 low dose

placebo tablets once daily

DRUG

Placebo identical to BI10773 high dose

placebo tablets once daily

Trial Locations (124)

Unknown

1245.20.10124 Boehringer Ingelheim Investigational Site, Mesa

1245.20.10108 Boehringer Ingelheim Investigational Site, Phoenix

1245.20.10150 Boehringer Ingelheim Investigational Site, Hot Springs

1245.20.10154 Boehringer Ingelheim Investigational Site, Chino

1245.20.10009 Boehringer Ingelheim Investigational Site, Santa Ana

1245.20.10131 Boehringer Ingelheim Investigational Site, West Hills

1245.20.10038 Boehringer Ingelheim Investigational Site, Northglenn

1245.20.10137 Boehringer Ingelheim Investigational Site, Clearwater

1245.20.10006 Boehringer Ingelheim Investigational Site, Miami

1245.20.10085 Boehringer Ingelheim Investigational Site, Plantation

1245.20.10078 Boehringer Ingelheim Investigational Site, Tampa

1245.20.10080 Boehringer Ingelheim Investigational Site, Decatur

1245.20.10128 Boehringer Ingelheim Investigational Site, Avon

1245.20.10060 Boehringer Ingelheim Investigational Site, Fishers

1245.20.10065 Boehringer Ingelheim Investigational Site, Indianapolis

1245.20.10117 Boehringer Ingelheim Investigational Site, Arkansas City

1245.20.10039 Boehringer Ingelheim Investigational Site, Wichita

1245.20.10146 Boehringer Ingelheim Investigational Site, Louisville

1245.20.10144 Boehringer Ingelheim Investigational Site, Watertown

1245.20.10115 Boehringer Ingelheim Investigational Site, Brick

1245.20.10129 Boehringer Ingelheim Investigational Site, Carlisle

1245.20.10045 Boehringer Ingelheim Investigational Site, Cincinnati

1245.20.10119 Boehringer Ingelheim Investigational Site, Cincinnati

1245.20.10130 Boehringer Ingelheim Investigational Site, Gallipolis

1245.20.10089 Boehringer Ingelheim Investigational Site, Houston

1245.20.10151 Boehringer Ingelheim Investigational Site, Hurst

1245.20.10155 Boehringer Ingelheim Investigational Site, San Antonio

1245.20.32008 Boehringer Ingelheim Investigational Site, Brussels

1245.20.32011 Boehringer Ingelheim Investigational Site, Brussels

1245.20.32023 Boehringer Ingelheim Investigational Site, Brussels

1245.20.32003 Boehringer Ingelheim Investigational Site, De Pinte

1245.20.32015 Boehringer Ingelheim Investigational Site, Deurne

1245.20.32016 Boehringer Ingelheim Investigational Site, Deurne

1245.20.32025 Boehringer Ingelheim Investigational Site, Gozée

1245.20.32022 Boehringer Ingelheim Investigational Site, Landen

1245.20.32019 Boehringer Ingelheim Investigational Site, Leopoldsburg

1245.20.32024 Boehringer Ingelheim Investigational Site, Linkebeek

1245.20.32021 Boehringer Ingelheim Investigational Site, Mouscron

1245.20.32027 Boehringer Ingelheim Investigational Site, Retie

1245.20.32020 Boehringer Ingelheim Investigational Site, Sint-Gillis-Waas

1245.20.32018 Boehringer Ingelheim Investigational Site, Tielt

1245.20.32026 Boehringer Ingelheim Investigational Site, Tremelo

1245.20.20011 Boehringer Ingelheim Investigational Site, Chilliwack

1245.20.20018 Boehringer Ingelheim Investigational Site, Victoria

1245.20.20015 Boehringer Ingelheim Investigational Site, Winnipeg

1245.20.20012 Boehringer Ingelheim Investigational Site, Moncton

1245.20.20016 Boehringer Ingelheim Investigational Site, Mount Pearl

1245.20.20008 Boehringer Ingelheim Investigational Site, St. John's

1245.20.20001 Boehringer Ingelheim Investigational Site, Barrie

1245.20.20019 Boehringer Ingelheim Investigational Site, Hamilton

1245.20.20010 Boehringer Ingelheim Investigational Site, London

1245.20.20017 Boehringer Ingelheim Investigational Site, London

1245.20.20003 Boehringer Ingelheim Investigational Site, Markham

1245.20.20009 Boehringer Ingelheim Investigational Site, Newmarket

1245.20.20013 Boehringer Ingelheim Investigational Site, Ottawa

1245.20.20005 Boehringer Ingelheim Investigational Site, Strathroy

1245.20.20002 Boehringer Ingelheim Investigational Site, Toronto

1245.20.20006 Boehringer Ingelheim Investigational Site, Toronto

1245.20.20014 Boehringer Ingelheim Investigational Site, Charlottetown

1245.20.20007 Boehringer Ingelheim Investigational Site, Montague

1245.20.20021 Boehringer Ingelheim Investigational Site, Trois-Rivières

1245.20.86007 Boehringer Ingelheim Investigational Site, Beijing

1245.20.86008 Boehringer Ingelheim Investigational Site, Beijing

1245.20.86001 Boehringer Ingelheim Investigational Site, Guangzhou

1245.20.86002 Boehringer Ingelheim Investigational Site, Guangzhou

1245.20.86003 Boehringer Ingelheim Investigational Site, Guangzhou

1245.20.86012 Boehringer Ingelheim Investigational Site, Guiyang

1245.20.86020 Boehringer Ingelheim Investigational Site, Hangzhou

1245.20.86049 Boehringer Ingelheim Investigational Site, Jinan

1245.20.86018 Boehringer Ingelheim Investigational Site, Jingzhou

1245.20.86019 Boehringer Ingelheim Investigational Site, Nanchang

1245.20.86010 Boehringer Ingelheim Investigational Site, Nanjing

1245.20.86043 Boehringer Ingelheim Investigational Site, Nanjing

1245.20.86016 Boehringer Ingelheim Investigational Site, Qingdao

1245.20.86004 Boehringer Ingelheim Investigational Site, Shanghai

1245.20.86005 Boehringer Ingelheim Investigational Site, Shanghai

1245.20.86006 Boehringer Ingelheim Investigational Site, Shanghai

1245.20.86057 Boehringer Ingelheim Investigational Site, Shenyang

1245.20.86017 Boehringer Ingelheim Investigational Site, Shiyan

1245.20.86013 Boehringer Ingelheim Investigational Site, Suzhou

1245.20.86015 Boehringer Ingelheim Investigational Site, Taiyuan

1245.20.86009 Boehringer Ingelheim Investigational Site, Wuhan

1245.20.86011 Boehringer Ingelheim Investigational Site, Xi'an

1245.20.86014 Boehringer Ingelheim Investigational Site, Xiamen

1245.20.49013 Boehringer Ingelheim Investigational Site, Dresden

1245.20.49016 Boehringer Ingelheim Investigational Site, Düsseldorf

1245.20.49015 Boehringer Ingelheim Investigational Site, Frankfurt

1245.20.49019 Boehringer Ingelheim Investigational Site, Haag

1245.20.49020 Boehringer Ingelheim Investigational Site, Hohenmölsen

1245.20.49014 Boehringer Ingelheim Investigational Site, Köthen

1245.20.49002 Boehringer Ingelheim Investigational Site, Neuwied

1245.20.49008 Boehringer Ingelheim Investigational Site, Nuremberg

1245.20.49017 Boehringer Ingelheim Investigational Site, Saint Ingbert/Oberwürzbach

1245.20.49022 Boehringer Ingelheim Investigational Site, Schauenburg

1245.20.49003 Boehringer Ingelheim Investigational Site, Unterschneidheim

1245.20.91005 Boehringer Ingelheim Investigational Site, Bangalore

1245.20.91006 Boehringer Ingelheim Investigational Site, Bangalore

1245.20.91008 Boehringer Ingelheim Investigational Site, Bangalore

1245.20.91003 Boehringer Ingelheim Investigational Site, Belagavi

1245.20.91004 Boehringer Ingelheim Investigational Site, Chennai

1245.20.91009 Boehringer Ingelheim Investigational Site, Chennai

1245.20.91002 Boehringer Ingelheim Investigational Site, Mumbai

1245.20.91007 Boehringer Ingelheim Investigational Site, Mumbai, Maharastra

1245.20.91010 Boehringer Ingelheim Investigational Site, Nagpur

1245.20.91001 Boehringer Ingelheim Investigational Site, Tamil Nadu

1245.20.35302 Boehringer Ingelheim Investigational Site, Co. Cork

1245.20.35305 Boehringer Ingelheim Investigational Site, Co. Galway

1245.20.35303 Boehringer Ingelheim Investigational Site, Co. Wexford

1245.20.35304 Boehringer Ingelheim Investigational Site, Offaly

1245.20.35306 Boehringer Ingelheim Investigational Site, Wexford

1245.20.81007 Boehringer Ingelheim Investigational Site, Chiyoda-ku, Tokyo

1245.20.81001 Boehringer Ingelheim Investigational Site, Chuo-ku, Tokyo

1245.20.81002 Boehringer Ingelheim Investigational Site, Chuo-ku, Tokyo

1245.20.81005 Boehringer Ingelheim Investigational Site, Ebetsu, Hokkaido

1245.20.81004 Boehringer Ingelheim Investigational Site, Kamakura, Kanagawa

1245.20.81003 Boehringer Ingelheim Investigational Site, Minato-ku, Tokyo

1245.20.81006 Boehringer Ingelheim Investigational Site, Shinjuku-ku, Tokyo

1245.20.81008 Boehringer Ingelheim Investigational Site, Shinjuku-ku, Tokyo

1245.20.81009 Boehringer Ingelheim Investigational Site, Suita, Osaka

1245.20.81010 Boehringer Ingelheim Investigational Site, Ube, Yamaguchi

1245.20.81012 Boehringer Ingelheim Investigational Site, Urasoe, Okinawa

1245.20.81013 Boehringer Ingelheim Investigational Site, Urasoe, Okinawa

1245.20.41004 Boehringer Ingelheim Investigational Site, Lugano

1245.20.41003 Boehringer Ingelheim Investigational Site, Rorschach

Sponsors
All Listed Sponsors
collaborator

Eli Lilly and Company

INDUSTRY

lead

Boehringer Ingelheim

INDUSTRY