NCT01172470View on ClinicalTrials.gov

Phase II Trial of Pemetrexed-Based Induction Chemotherapy Followed by Concomitant Chemoradiotherapy in Previously Irradiated Head and Neck Cancer Patients

PHASE2CompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

June 30, 2005

Primary Completion Date

June 30, 2007

Study Completion Date

July 31, 2010

Conditions
Head and Neck Cancer
Interventions
DRUG

Gemcitabine

4 doses of induction chemotherapy every 2weeks, IV (in the vein)

DRUG

Pemetrexed

"Induction Chemotherapy:~4 doses of induction chemotherapy every 2weeks(Days 1, 15, 28, and 42), through an infusion for approximately 10 minutes.~Chemoradiotherapy:~Day 1,22, and 43through IV infusion over a period of 10 minutes"

DRUG

Carboplatin

"Chemoradiotherapy:~Day 1, 22 and 4 through IV infusion over a period of 1 hour."

Trial Locations (1)

60653

The University of Chicago Medical Center, Chicago

All Listed Sponsors
lead

University of Chicago

OTHER

NCT01172470 - Phase II Trial of Pemetrexed-Based Induction Chemotherapy Followed by Concomitant Chemoradiotherapy in Previously Irradiated Head and Neck Cancer Patients | Biotech Hunter | Biotech Hunter