Effect of Atypical Antipsychotic Drugs Olanzapine and Amisulpride on Glucose Metabolism

euglycemic hyperinsulinemic clamp with target blood glucose of 90 mg/dl (5 mmol/l), followed by hyperglycemic clamp, target blood glucose of 180 mg/dl (10 mmol/l) for measurement of insulin sensitivity and insulin secretion

Single dose of amisulpride 200 mg p.o. given at 8:00 a.m.

Single dose of olanzapine 10 mg p.o. given at 8:00 a.m.

Placebo capsules are given at 8:00 a.m.