610
Participants
Start Date
July 31, 1994
Primary Completion Date
October 31, 1998
Study Completion Date
March 31, 2012
cisplatin
100 mg/m2 i.v. over 30-60 minutes, days 1 \& 29
Etoposide
Oral etoposide given 50 mg b.i.d. X 10 only on RT treatment days 1-5, 8-12, 29-33, and 36-40. 75 mg/day if body surface area \< 1.7 m2
Vinblastine
5 mg/m2 i.v. bolus weekly first 5 weeks of RT
Radiation therapy
63 Gy/7 wks/34 daily fractions (1.8 Gy X 25 fx then 2.0 Gy X 9 fX) beginning day 50 of protocol treatment
Cisplatin
50 mg/m2 i.v. over 30-60 minutes on days 1, 8, 29, and 36
Radiation therapy
63 Gy/7 wks/34 daily fractions (1.8 Gy X 25 fx then 2.0 Gy X 9 fx) beginning day 1 of protocol treatment
Radiation therapy
69.6 Gy/6 wks/58 X 1.2 Gy twice daily fractions (at least 6 hours apart) beginning day 1 of protocol therapy
Collaborators (1)
National Cancer Institute (NCI)
NIH
NRG Oncology
OTHER
Radiation Therapy Oncology Group
NETWORK