Ascending Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Evolocumab (AMG 145) in Adults With Hyperlipidemia on Stable Doses of a Statin

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

June 1, 2010

Primary Completion Date

September 14, 2011

Study Completion Date

September 14, 2011

Conditions

Hyperlipidemia

Interventions

BIOLOGICAL

Evolocumab

Administered by subcutaneous injection

BIOLOGICAL

Placebo

Administered by subcutaneous injection