Gabapentin Versus Transdermal Fentanyl Matrix for Chronic Neuropathic Pain

PHASE4CompletedINTERVENTIONAL
Enrollment

108

Participants

Timeline

Start Date

May 31, 2010

Primary Completion Date

November 30, 2011

Study Completion Date

November 30, 2011

Conditions
Neuropathic PainSpinal Stenosis
Interventions
DRUG

transdermal fentanyl matrix, gabapentin

"transdermal fentanyl matrix: during 1st to 6th days, 12ug/h of fentanyl matrix will be applied. During 7th to 28th days, the dosage of fentanyl matrix will be increased until the pain score decrease not more than 2 every 6 days. The maximal dosage is 100ug/h. During 29th to 56th days, the dosage will be maintained.~Gabapentin: the 1st day, 300mg hs, the 2nd day, 300mg bid, the 3th to 4th days, 300mg tid, the 5th to 6th days, 300mg-300mg-600mg the 7th to 28 days, the dosage will be increased until the pain score decreased not more than 2 and the maximal dose is 2400mg per day. During 29th to 56th days, the dosage will be maintained."

Trial Locations (1)

156-707

Seoul National University, College of Medicine, Department of Orthopedic Surgery, SMG-SNU Boramae Medical Center, Seoul

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Seoul National University Bundang Hospital

OTHER

collaborator

Asan Medical Center

OTHER

collaborator

Inje University

OTHER

collaborator

Chonnam National University Hospital

OTHER

collaborator

Chung-Ang University Hosptial, Chung-Ang University College of Medicine

OTHER

collaborator

Dankook University

OTHER

lead

Seoul National University Hospital

OTHER