Effect of QVA149 Versus NVA237 and Tiotropium on Chronic Obstructive Pulmonary Disorder (COPD) Exacerbations

PHASE3CompletedINTERVENTIONAL
Enrollment

2,224

Participants

Timeline

Start Date

April 30, 2010

Primary Completion Date

July 31, 2012

Study Completion Date

July 31, 2012

Conditions
Chronic Obstructive Pulmonary Disease
Interventions
DRUG

QVA149

QVA149 110/50 μg capsules for inhalation, once daily delivered via Novartis Single Dose Dry Powder Inhaler (SDDPI) for at least 64 weeks of double blind treatment period (study duration was up to 76 weeks).

DRUG

NVA237

NVA237 50 μg capsules for inhalation, once daily delivered via Novartis Single Dose Dry Powder Inhaler (SDDPI) for at least 64 weeks of double blind treatment period (study duration was up to 76 weeks).

DRUG

tiotropium

Open-label tiotropium bromide 18 μg capsules for inhalation once daily delivered via HandiHaler® device for at least 64 weeks of double blind treatment period (study duration was up to 76 weeks).

DRUG

Salbutamol/albuterol

As needed throughout the study

Trial Locations (342)

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Novartis Investigative Site, San Isidro

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